| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
In this study, we examined if a recently discovered controllable self-assembly of TiO2 nanonodules (micro-nano hybrid surface) has affected to determine the biological capability of titanium surfaces and their responsiveness to UV treatment. Although UV treatment increased the attachment, spread, proliferation, and mineralization of osteoblastic cells on all titanium surfaces, these effects were more accentuated on nanonodular surfaces than on surfaces with micropits alone and were disproportionate depending on nanonodule sizes. The effect of UV treatment can be multiplied on micro-nano hybrid titanium surfaces compared with the surfaces with micropits alone. Among the nanonodules tested in this study, 300-nm nodules seemed to create the most effective morphological environment for responding to UV-treatment..
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