| Project/Area Number |
23592993
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
TAKECHI Masaaki 広島大学, 医歯薬保健学研究院, 准教授 (00304535)
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| Co-Investigator(Kenkyū-buntansha) |
KAMATA Nobuyuki 広島大学, 医歯薬保健学研究院, 教授 (70242211)
OHTA Kouji 広島大学, 病院, 助教 (20335681)
NAKAGAWA Takayuki 広島大学, 病院, 病院助教 (30456230)
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| Co-Investigator(Renkei-kenkyūsha) |
ISHIKAWA Kunio 九州大学, 歯学研究科, 教授 (90202952)
TSURU Kanji 九州大学, 歯学研究科, 准教授 (50314654)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 複合膜 / 骨置換 / 骨伝導 / 破骨細胞 / 骨造成 / インプラント / オッセオインテグレーション / 骨伝導性 / 炭酸アパタイト |
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| Research Abstract |
We developed the GBR membrane which has not only the function to interrupt an epithelium cell but also an increase and the differentiation of the osteoblasts positively, and the resolution was absorbed in harmony with finally bone remodeling in vivo, and was completely substituted for a bone by making CO3Ap and various cell growth factors composition in biodegradable high polymer PLGA. Furthermore, using a cell and a laboratory animal, I demonstrated the usefulness of the materials which I developed.
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