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Elucidation of interaction between tooth guide girdle and dental follicle related to tooth eruption and root resorption mechanism accompany with abnormal teeth eruption

Research Project

Project/Area Number 23593022
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

MATSUMOTO Yoshiro  東京医科歯科大学, 歯学部附属病院, 講師 (20292980)

Co-Investigator(Kenkyū-buntansha) ONO Takashi  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30221857)
KANEKO Sawa  東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (80372449)
HOSOMICHI Jun  東京医科歯科大学, 大学院医歯学総合研究科, 講師 (00420258)
Co-Investigator(Renkei-kenkyūsha) KANEKO Sawa  東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (80372449)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords生理的歯根吸収 / 乳歯 / 永久歯 / 歯胚 / 歯小嚢 / 歯根形成 / 歯根吸収 / 埋伏歯 / バイオインテグレーション
Outline of Final Research Achievements

To clarify the physiological mechanism of permanent teeth eruption which leads to the elucidation of the pathological situation in the stage of anterior teeth exchange, various morphological examinations about the bovine deciduous teeth and succeeding permanent teeth in each developmental stage were performed.
As a result, resorption of the deciduous teeth by a permanent teeth germ was observed, and the structure considered to the tooth guide girdle with the alveolar bone socket of a deciduous tooth root and a succeeding permanent tooth germ in the alveolar bone space was also observed. Moreover, correlations between the amount of root resorption of deciduous tooth, the amount of alveolar bone resorption, the amount of succeeding permanent tooth root formation and the degree of tooth mobility were observed.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (14 results)

All 2015 2014 2013 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (5 results) Remarks (1 results)

  • [Journal Article] Impairment of nasal airway under intermittent hypoxia during growth period in rats.2014

    • Author(s)
      Yoichiro Kuma, Risa Usumi-Fujita, Jun Hosomichi, Shuji Oishi, Hideyuki Maeda, Hisashi Nagai, Yasuhiro Shimizu, Sawa Kaneko, Chisa Shitano, Jun-ichi Suzuki, Ken-ichi Yoshida, Takashi Ono
    • Journal Title

      Arch. Oral Biol.

      Volume: 59 Pages: 1139-1145

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Mechanical loading leads to osteoarthritis-like changes in the hypofunctional temporomandibular joint in rats.2014

    • Author(s)
      Yuhei Ikeda, Ikuo Yonemitsu, Maki Takei, Shunichi Shibata, Takashi Ono
    • Journal Title

      Arch. Oral Biol.

      Volume: 59 Pages: 1368-1376

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Soft Tissue Cephalometric Norms for Orthognathic and Cosmetic Surgery.2013

    • Author(s)
      Shindoi JM, Matsumoto Y, Sato Y, Ono T, Harada K.
    • Journal Title

      Journal of Oral and Maxillofacial Surgery

      Volume: 71

    • Related Report
      2013 Research-status Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Occlusal hypofunction causes periodontal atrophy and VEGF/VEGFR inhibition in tooth movement.2013

    • Author(s)
      Usumi-Fujita R, Hosomichi J, Ono N, Shibutani N, Kaneko S, Shimizu Y, Ono T.
    • Journal Title

      Angle Orthod.

      Volume: 83 Pages: 48-56

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of a surgical procedure for biointegration of a newly designed orthodontic onplant2012

    • Author(s)
      Kiyomi Sakamoto-Ozaki,Yoshiro Matsumoto, Zuisei Kanno,Jun-ichiro lida,Kunimichi Soma
    • Journal Title

      Orthodontics

      Volume: 13 Pages: 216-225

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of sympathetic nervous activity on alveolar bone loss induced by occlusal hypofunction in rats.2011

    • Author(s)
      Shimizu Y, Hosomichi J, Kaneko S, Shibutani N, Ono T.
    • Journal Title

      Arch Oral Biol.

      Volume: 56 Pages: 1404-1411

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Intermittent posterior displacement of the rat mandible in the growth period affects the condylar cancellous bone.2011

    • Author(s)
      Kuroda Y, Yonemitsu I, Hosomichi J, Watari I, Takei M, Ishida Y, Ono T.
    • Journal Title

      Angle Orthod.

      Volume: 81 Pages: 975-982

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes in the microstructure of the rat alveolar bone induced by unilateral molar extraction and estrogen deficiency.2011

    • Author(s)
      Honda K, Watari I, Takei M, Ono T.
    • Journal Title

      Orthod Waves.

      Volume: 70 Pages: 143-150

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] ROOT RESORPTION OF MAXILLARY INCISORS ASSOCIATED WITH ECTOPICALLY ERUPTING CANINES: PREDISPOSING FACTORS, DIAGNOSIS AND PROGNOSIS OF ORTHODONTIC TREATMENT2015

    • Author(s)
      Matsumoto Y., Hoshomichi J., Ishida Y., Ohmori H., Shimizu Y., Kyuragi T., Shitano C., Kawabe A., Maekawa M., Ikeda Y., Kirii A, Kita S., Sakaguchi T., An J., Yamada K., Suzuki K, Ono T.
    • Organizer
      8th Intenational Orthodontic Congress
    • Place of Presentation
      London, England
    • Year and Date
      2015-09-27 – 2015-09-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 矯正歯科診療を受けたトップアスリートに関する施設内統計学的調査・検討2013

    • Author(s)
      松本芳郎、豊島由佳子、添島沙夜香、田中沙織、川原 貴
    • Organizer
      第24回日本臨床スポーツ医学会学術集会
    • Place of Presentation
      熊本
    • Related Report
      2013 Research-status Report
  • [Presentation] 咬合刺激低下歯の矯正学的移動に伴う歯槽骨の変化について2012

    • Author(s)
      舌野 知佐, 馬場 麻人, 金香 佐和, 細道 純, 渋谷 直樹, 清水 康広, 臼見 莉沙, 高野 吉郎, 小野卓史
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2012 Research-status Report
  • [Presentation] 軟性飼料飼育した成長期ラットの歯槽骨は上下顎骨において異なる構造変化を示す2012

    • Author(s)
      清水 康広, 石田 宝義, 細道 純, 金香 佐和, 小野 卓史
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2012 Research-status Report
  • [Presentation] Severe root resorption of four maxillary incisors and bilateral canine impaction: An interdisciplinary approach2011

    • Author(s)
      Yoshiro MATSUMOTO, Takashi ONO
    • Organizer
      The 4th International Congress & The 70th Annual Meeting of the Japanese Orthodontic Society
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Remarks] 東京医科歯科大学 研究情報データベース

    • URL

      http://reins.tmd.ac.jp/search?m=home&l=ja

    • Related Report
      2014 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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