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Regeneration of Condyle with Mandibular Advancement

Research Project

Project/Area Number 23593030
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionHiroshima University

Principal Investigator

FUJITA TADASHI  広島大学, 医歯薬保健学研究院, 助教 (90335662)

Co-Investigator(Kenkyū-buntansha) SHIRAKURA Maya  広島大学, 大学院医歯薬保険学研究院, 助教 (70549013)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords下顎頭再生 / 機能的矯正装置
Research Abstract

The aim of this study was to examine the function of the articular disk in regeneration of condyle after unilateral condylectomy with use of a functional appliance in growing rats. The unilateral condylectomy + discectomy produced reduced growth of the mandible. However, the reduced growth of the mandible was not eliminated even by the use of the functional appliance. Regeneration of the condyle was demonstrated in all the rats in the condylectomy and condylectomy + appliance groups. The shape of condyle in all the rats in the condylectomy + appliance group was exactly equivalent to the normal condyles, whereas the shape was deformed in the condylectomy group. Four layers of the condylar cartilage were also clearly detected in the condylectomy + appliance group. However, the regeneration of condyle was not observed in the two discectomy groups even by using the functional appliance by means of histomorphometric analyses.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (11 results)

All 2013 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (7 results)

  • [Journal Article] Regeneration of condyle with a functional appliance2013

    • Author(s)
      Fujita T, Hayashi H, Shirakura M, Tsuka Y, Fujii E, Kawata T, Kaku M, Ohtani J, Motokawa M, Tanne K
    • Journal Title

      J Dent Res

      Volume: 92 Pages: 322-328

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the lip-line in asymmetrical cases treated with isolated mandibular surgery2013

    • Author(s)
      Fujita T, Shirakura M, Koh M, Itoh G, Hayashi H, Tanne K
    • Journal Title

      J Orthod

      Volume: 40 Pages: 313-317

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Regeneration of condyle with a functional appliance2013

    • Author(s)
      Fujita T, Hayashi H, Shirakura M, Tsuka Y, Fujii E, Kawata T, Kaku M, Ohtani J, Motokawa M, Tanne K.
    • Journal Title

      Journal of Dental Research

      Volume: 92 Issue: 4 Pages: 322-328

    • DOI

      10.1177/0022034513480795

    • Related Report
      2013 Annual Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes in the lip-line in asymmetrical cases treated with isolated mandibular surgery.2013

    • Author(s)
      Fujita T, Shirakura M, Koh M, Itoh G, Hayashi H, Tanne K.
    • Journal Title

      J Orthod.

      Volume: 40 Issue: 4 Pages: 313-317

    • DOI

      10.1179/1465313313y.0000000056

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Regeneration of Condyle with Mandibular Advancement2013

    • Author(s)
      Fujita T, Hayashi H, Shirakura M, Tsuka Y, Fujii E, Tanne K
    • Organizer
      第113回アメリカ矯正歯科学会大会
    • Place of Presentation
      Philadelphia Convention Center, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Regeneration of Condyle Needs the Articular Disk2013

    • Author(s)
      Hayashi H, Fujita T, Fang X, Shirakura M, Tsuka Y, Fujii E, Tanne K
    • Organizer
      第113回アメリカ矯正歯科学会大会
    • Place of Presentation
      Philadelphia Convention Center, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Regeneration of Condyle with Mandibular Advancement2013

    • Author(s)
      Tadashi Fujita, H Hayashi, M Shirakura, Y Tsuka, E Fujii, K Tanne
    • Organizer
      第113回アメリカ矯正歯科学会大会
    • Place of Presentation
      Philadelphia Convention Center, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] REGENERATION OF CONDYLE NEEDS THE ARTICULAR DISK2013

    • Author(s)
      Hidetaka Hayashi, T Fujita, X Fang, M Shirakura, Y Tsuka, E Fujii, K Tanne
    • Organizer
      第113回アメリカ矯正歯科学会大会
    • Place of Presentation
      Philadelphia Convention Center, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Regeneration of condyle by use of a functional appliance2012

    • Author(s)
      Fujita T.
    • Organizer
      8th Asian Pacific Orthodontic Conference 47th Indian Orthodontic Conference
    • Place of Presentation
      New Delhi, India
    • Related Report
      2012 Research-status Report
  • [Presentation] 下顎骨の成長発育に対する関節円板の重要な役割2012

    • Author(s)
      藤田 正, 林 英貴, 方 肖, 白倉麻耶, 柄 優至, 藤井絵理, 丹根一夫
    • Organizer
      第25回日本顎関節学会・学術大会
    • Place of Presentation
      札幌
    • Related Report
      2012 Research-status Report
  • [Presentation] 機能的矯正装置による下顎頭再生過程の組織学的検討2012

    • Author(s)
      林 英貴, 藤田 正, 白倉麻耶, 柄 優至, 方 肖, 藤井絵理, 丹根一夫
    • Organizer
      第71回日本矯正歯科学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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