| Project/Area Number |
23593034
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MIYAWAKI Shouichi 鹿児島大学, 大学院歯学総合研究科, 教授 (80295807)
OHMURE Haruhito 鹿児島大学, 大学院歯学総合研究科, 講師 (00404484)
SUENAGA Shigeaki 鹿児島大学, 医学部・歯学部附属病院, 講師 (00136889)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | fMRI / ブラキシズム / ストレス / 酸知覚 / 脳機能 / 脳 |
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| Research Abstract |
In the present study, the below results were derived masseter muscle activity and cerebral activation during stress by calculation task, fist clenching, and experimental esophageal acidification to the healthy adults. (1) Masseter muscle activities during calculation task and fist clenching were increased significantly. (2) Cerebral activations were observed during calculation task and fist clenching in insula and anterior cingulate cortex. (3) The results of the investigation of the effects of intra-esophageal infusions of 5 mL acidic solution (0.1 N HCl) or saline suggested that awake bruxism episodes were induced by esophageal acidification.
Both the insula and the anterior cingulate cortex have been also reported to activate during acid stimulation to the esophagus. Therefore, these researches show that the increase of masseter muscle activities (Bruxism) during stress and esophageal acidification were caused by cerebral activation of insula and anterior cingulate cortex.
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