The etiology of dental caries may need to be refined: Based on the analysis of oral microbiome.
| Project/Area Number |
23593043
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Orthodontic/Pediatric dentistry
|
|---|
| Research Institution | Tokyo Dental College |
|---|
Principal Investigator |
SAKURAI ATSUO 東京歯科大学, 歯学部, 講師 (90431759)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SHINTANI Seikou 東京歯科大学, 歯学部, 教授 (90273698)
MARUYAMA Fumito 東京医科歯科大学, 医歯学総合研究科, 准教授 (30423122)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
|---|
| Keywords | 口腔内細菌 / レンサ球菌 / 乳酸桿菌 / 齲蝕 / 口腔疾患 / 口腔内細菌叢 / 哺乳齲蝕 |
|---|
| Research Abstract |
From 130 children, aged 2-7 years old, swab samples of teeth surfaces were collected after parental informed consent was obtained. Among Lactobacillus species, Lactobacillus salivarius was most frequently identified, followed by L. casei, L. fermentum, and L. gasseri. Especially, L. fermentum was predominantly identified from samples with high caries prevalence (dmf >6). Genetic diversity among the same Lactobacillus species in an individual sample is also related to high caries prevalence. In addition, analysis of oral microbiota in swab samples from children and their mothers revealed that oral microbiota in children showed much more abundance and diversity than in mothers. These characteristics might influence on a susceptibility of dental caries during early childhood age.
|
Report
(4 results)
Research Products
(54 results)
-
-
[Journal Article] 歯科大学病院小児歯科における初診患者の実態調査2014
Author(s)
岩田美奈子,小鹿裕子,浦野絢子,荒井亮,山頭亜里沙,隝田みゆき,辻野啓一郎,櫻井敦朗,大多和由美,新谷誠康,山下秀一郎
-
Journal Title
小児歯科学雑誌
Volume: 52(1)
Pages: 47-53
NAID
Related Report
Peer Reviewed
-
[Journal Article] 歯科大学病院小児歯科における低年齢児齲蝕の実態調査2014
Author(s)
小鹿裕子,岩田美奈子,浦野絢子,荒井亮,山頭亜里沙,隝田みゆき,辻野啓一郎,櫻井敦朗,大多和由美,新谷誠康,山下秀一郎
-
Journal Title
小児歯科学雑誌
Volume: 52(1)
Pages: 54-61
NAID
Related Report
Peer Reviewed
-
-
-
[Journal Article] 歯科大学病院小児歯科における初診患者の実態調査2014
Author(s)
岩田美奈子, 小鹿裕子, 浦野絢子, 荒井亮, 山頭亜里沙, 隝田みゆき, 辻野啓一郎, 櫻井敦朗, 大多和由美, 新谷誠康, 山下秀一郎.
-
Journal Title
小児歯科学雑誌
Volume: 52
Pages: 47-53
NAID
Related Report
Peer Reviewed
-
[Journal Article] 歯科大学病院小児歯科における低年齢児齲蝕の実態調査2014
Author(s)
小鹿裕子, 岩田美奈子, 浦野絢子, 荒井亮, 山頭亜里沙, 隝田みゆき, 辻野啓一郎, 櫻井敦朗, 大多和由美, 新谷誠康, 山下秀一郎.
-
Journal Title
小児歯科学雑誌
Volume: 52
Pages: 54-61
NAID
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] わが国におけるMolar Incisor Hypomineralization (MIH)の実態調査.第一報MIHの発症頻度と重症度について2013
Author(s)
新居由紀,桜井敦朗,今井裕樹,中内彩乃,江木勝彦,米倉智子,石岡みずき,本間宏実,児島泰子,熊澤海道,山下治人,泉水祥江,米津卓郎,杉山精一,新谷誠康
Organizer
第51回日本小児歯科学会
Place of Presentation
岐阜
Year and Date
2013-05-23
Related Report
-
[Presentation] わが国におけるMolar Incisor Hypomineralization (MIH)の実態調査.第二報MIH発症に影響を与える要因の解析2013
Author(s)
本間宏実,今井裕樹,桜井敦朗,中内彩乃,江木勝彦,新居由紀,米倉智子,石岡みずき,児島泰子,熊澤海道,山下治人,泉水祥江,米津卓郎,杉山精一,新谷誠康
Organizer
第51回日本小児歯科学会
Place of Presentation
岐阜
Year and Date
2013-05-23
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 全身麻酔下での歯科治療後、強度の非協力となった2症例2011
Author(s)
松本直人, 松浦信幸, 赤瀬眞五, 阪柳敏春, 菊田高行, 戸坂清二, 丸山清孝, 西尾智見, 野田幸枝, 桜井敦朗, 今井裕樹, 新谷誠康, 一戸達也
Organizer
日本障害者歯科学会
Place of Presentation
福岡
Related Report
-
-
-
-
-
-
-
-
-
-
