| Project/Area Number |
23593249
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Clinical nursing
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| Research Institution | Osaka City University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
USAMI Makoto 神戸大学, 保健学研究科, 教授 (00193855)
KATAYAMA Megumi 神戸大学, 保健学研究科, 講師 (60295772)
WAKITA Kumiko 神戸大学, 医学部附属病院, 管理栄養士 (90540138)
NIBU Kenichi 神戸大学, 医学系研究科(研究院), 教授 (20251283)
SAITOU Miki 神戸大学, 医学系研究科(研究院), 講師 (30335442)
YAMANE Hideo 大阪市立大学, 大学院医学系研究科, 教授 (60145787)
IGUCHI Hiroyoshi 大阪市立大学, 大学院医学系研究科, 講師 (70271195)
YADA Mamiko 関東学院大学, 看護学部, 教授 (10239783)
FUKUDA Atsuko 神戸大学, 保健学研究科, 講師 (80294239)
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| Co-Investigator(Renkei-kenkyūsha) |
KATAYAMA Osamu 神戸市看護大学, 看護学部, 助教 (20295778)
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| Research Collaborator |
AKAHANI Shirou NTT西日本大阪病院, 耳鼻咽喉科, 医師
TAKAHASHI Miki 神戸大学, 医学部附属病院, 言語聴覚士
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 中咽頭癌 / 化学療法併用放射線治療 / QOL / 味覚異常 / 有害事象 / 低栄養 / 味覚障害 / 経皮内視鏡的胃瘻造設術 / 献立 / 化学療法併用放射線療法 / 栄養状態 / 経皮内視鏡的胃瘻増設術 / 味覚 / 栄養 / PEG / 唾液 |
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| Research Abstract |
Chemo-radiotherapy (CRT)is highly efficacious in the treatment of oropharyngeal cancer patients, but is accompanied by a high incidence of adverse events. In this study, we followed adverse events and changes in the QOL status associated with CRT over a long term. The results revealed that adverse events occurred at a radiation dose of 20 Gy or higher and they did not disappear even 9 months after the CRT completion. The body weight of the patients also decreased substantially.Patients' QOL was found not to recover after CRT within the studied period. These findings confirm that active interventions on the patients are required even after the CRT completion.
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