| Project/Area Number |
23593344
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | International University of Health and Welfare |
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Principal Investigator |
HORIGANE Yukie 国際医療福祉大学, 保健医療学部, 講師 (90588857)
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| Co-Investigator(Kenkyū-buntansha) |
高橋 眞理 (高橋 真理) 北里大学, 看護学部 (20216758)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
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| Keywords | 早産児 / 光環境 / ストレス / 唾液クロモグラニンA / 自律神経活動 / 早産児行動評価 / 光 / 唾液分析 / 自律神経 / 行動評価 / 自律神経活動評価 / コルチゾール / 心拍変動解析 |
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| Research Abstract |
Objective:This study aimed to evaluate the influence of low and normal illumination during fundus examination on the stress response in premature infants through the evaluation of saliva, behavior, and autonomic nervous activity reflected by heart rate variability.Methods: A total of 36 premature infants who were born at an average gestational age of 29.4 weeks (25.2 weeks-34.6 weeks) with an average birth weight of 1,296 g (727-2,146 g) were included in this study. All infants underwent fundus examination with the induction of mydriasis under normal illumination(control group) or low illumination (intervention group), and salivary chromogranin A levels, behavior, and heart rate variability were analyzed before and until 6 hours after the induction of mydriasis.Results: The mean salivary chromogranin A levels were significantly lower(40.51 +- 40.796 pmol/mg) in the intervention group than in the control group in (167.72 +- 84.634pmol/mg ; p < .05; t-test).
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