Development and validation of a biomarker-based long-term support program for smoking cessation during pregnancy/lactation period
| Project/Area Number |
23593359
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | International University of Health and Welfare (2013-2014)
Fukuoka University (2011-2012) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKASIMA Emiko 国際医療福祉大学, 保健医療学部, 教授 (30461536)
SAKUMA Yoshiko 福岡大学, 医学部, 准教授 (80554758)
嶋松 陽子 活水女子大学, 看護学部, 教授 (80270099)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Keywords | 禁煙 / 妊産婦 / コチニン / 受動喫煙 / バイオマーカー / 能動喫煙 / 喫煙 / 精密酸化脂質物質 / 酸化ストレス物質 |
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| Outline of Final Research Achievements |
Smoking cessation support for women in their 20s and 30s is crucial for the optimal development of the next generation. The present study aimed to develop and validate biomarker indices of the ill effects of smoking to motivate expectant and nursing mothers to stop smoking.
Exploratory study was conducted to evaluate the active/passive smoking-derived cotinine levels and breath CO concentration in maternal blood, urine, and umbilical cord blood between pregnancy period and one-month postpartum checkup. The conditions of labor and delivery were also explored. On the basis of the obtained results, personalized biomarker change indices were created because of the individual differences in the smoking status and cotinine levels in maternal blood, urine, and umbilical cord blood. Future studies should aim to use and validate the effects of these biomarkers for group guidance of women before pregnancy and for individual guidance of smokers.
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Report
(5 results)
Research Products
(5 results)
