| Project/Area Number |
23593457
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Community health/Gerontological nurisng
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| Research Institution | Aichi Prefectural University |
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Principal Investigator |
KUMAZAWA YUKI 愛知県立大学, 看護学部, 客員共同研究員 (20571730)
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| Co-Investigator(Kenkyū-buntansha) |
KAMAKURA Yayoi 愛知県立大学, 看護学部, 教授 (00177560)
FUKADA Junko 愛知県立大学, 看護学部, 教授 (60238441)
YONEDA Masahiko 愛知県立大学, 看護学部, 教授 (80201086)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 高齢者 / 市中肺炎 / 唾液タンパク / 肺炎球菌 / 肺炎球菌ワクチン / 地域高齢者 / 予防 / 唾液 / 口腔内環境 / 口腔内細菌 / real-time PCR法 |
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| Research Abstract |
We clarified the saliva protein concentrations (secretory immunoglobulin A: sIgA; lactoferrin: LF; epidermal growth factor: EGF) which controlled to intraoral bacteria, and Streptococcus pneumoniae carrying germs for a normal adults and a local community elderly, as a basic research for the community-acquired pneumonia prevention. And we examined the association of a concentration of saliva protein with age, Streptococcus pneumoniae carrying germs and pneumococcus vaccination.
An adult group was the highest in the ratio of Streptococcus pneumoniae carriers (55.6%). The concentrations of sIgA, LF, EGF were higher in the adult group than the older adult and old-old groups. No association was found between the pneumococcus vaccination factor and the sIgA concentration. As for non-carrying and carrying group among the elderly, non-carrying were higher than those carrying in sIgA, LF (old-old group), and EGF concentration.
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