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Improved input-function quantification in a noninvasive measurement using medical tomography

Research Project

Project/Area Number 23602001
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics/Radiological Technology
Research InstitutionHokkaido University

Principal Investigator

KUBO Naoki  北海道大学, 安全衛生本部, 特任准教授 (80241389)

Co-Investigator(Kenkyū-buntansha) SHIGA Tohru  北海道大学, 大学院医学研究科, 准教授 (80374495)
Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords入力関数 / ファントム / 超音波診断装置 / PET / 繰り返し精度
Outline of Final Research Achievements

Medical tomography can provide quantitative estimates of physiological or metabolic parameters. This usually requires obtaining multiple arterial blood samples during dynamic scans. As this procedure is considered a health risk for the patient and medical personnel, a measurement of arterial tracer concentration using medical tomography has been devised that can be used to obtain an input function with minimum discomfort to the patient and without drawing arterial blood. However, measured input functions in medical tomography are influenced by disturbing factors. We have developed a phantom of an arterial input-function. Correction-coefficients of the input function were obtained by means of this phantom. Thus, a measurement of arterial tracer concentration as an input function has been improved by correction-coefficients using our phantom.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (5 results)

All 2014 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results) (of which Invited: 3 results)

  • [Journal Article] Evaluation of delineation of image details in semiconductor PET utilizing the normalized mutual information technique2014

    • Author(s)
      Kubo N, Hirata K, Matsuzaki K, Morimoto Y, Takeuchi W, Hattori N, Shiga T, Kuge Y, Tamaki N
    • Journal Title

      Nuclear Medicine Communications

      Volume: 35 Issue: 6 Pages: 677-682

    • DOI

      10.1097/mnm.0000000000000085

    • NAID

      120005607879

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] 放射線障害防止を見据えての画像処理-逐次近似再構成法および画像重ね合わせによる貢献-2014

    • Author(s)
      久保直樹
    • Organizer
      第17回道東放射線技術懇話会
    • Place of Presentation
      釧路市生涯学習センター(釧路市)
    • Year and Date
      2014-10-04
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 把握しておきたい物理に関する知識:減弱補正2013

    • Author(s)
      久保直樹
    • Organizer
      第13回札幌核医学技術研究会
    • Place of Presentation
      北海道大学(札幌市)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Medical Image Reconstruction: Concepts and Methods2012

    • Author(s)
      Kubo N
    • Organizer
      2012 CIS Workshop  -Imaging and Applications in Isotope Sciences-
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] A phantom study of repeatability of an intratumoral inhomogeneity index in FDG-PET2012

    • Author(s)
      Kubo N, Iwahashi H, Yakabe R, Kuge Y
    • Organizer
      Annual Congress of the European Association of Nuclear Medicine 2012
    • Place of Presentation
      Milano Congressi, Milan, Italy
    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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