| Project/Area Number |
23602002
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical Physics/Radiological Technology
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| Research Institution | Yamagata University |
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Principal Investigator |
YUASA Tetsuya 山形大学, 理工学研究科, 教授 (30240146)
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| Co-Investigator(Renkei-kenkyūsha) |
ANDO Masami 東京理科大学, 総合研究機構, 教授 (30013501)
ICHIHARA Shu 名古屋医療センター, 臨床研究センター, 室長 (30426499)
HUO Qinghai ㈱東芝メディカル
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 屈折 / CT再構成 / 乳がん / 放射光X線 / 早期診断 / 屈折コントラスト / コンピューテッド・トモグラフィー / ラウエ結晶アナライザー / 放射光 / 乳癌 |
|---|
| Research Abstract |
We proposed a novel x-ray CT imaging method based on phase contrast, which employs a Laue-case analyzer composed of Si single-crystal thin plate and two CCD cameras positioned downstream of the analyzer. In addition, we devised a data processing algorithm to extract refraction angle deviation from the incident beam direction, and a 3 dimensional CT reconstruction algorithm to reconstruct the refraction index distribution in a sample from the projections of refraction angle deviation. We demonstrated the effectiveness from the viewpoints of theory, simulation, and experiment. We clearly delineated TDLU (Terminal Duct Lobular Unit) in a pathological sample at a resolution of 10 microns.
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