Pioneering Research on Manufacturability of Radionuclides for Nuclear Medicine by Fast Neutrons

• Project/Area Number: 23602015
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical Physics/Radiological Technology
• Research Institution: Japan Atomic Energy Agency
• Principal Investigator: IWAMOTO NOBUYUKI 独立行政法人日本原子力研究開発機構, 原子力科学研究部門 原子力基礎工学研究センター, 研究副主幹 (70391307)
• Co-Investigator(Kenkyū-buntansha): IWAMOTO Osamu 独立行政法人日本原子力研究開発機構, 原子力科学研究部門原子力基礎工学研究センター, 研究主幹 (80370360)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 核医学 / 核データ評価 / 放射性同位元素 / ＲＩ生成断面積 / 放射能 / 画像診断 / RI生成断面積 / RI生成量

Research Abstract

In order to produce radioisotopes (RIs) for nuclear medicine by using intense fast neutrons in Japan, we evaluated nuclear reaction cross sections for the production of RIs (gamma-ray, beta-ray and positron emission nuclides) which are suitable for nuclear medical care. We calculated the radioactivity of produced RIs by simulating a realistic RI-production system. We took account of the manufacturability of all RIs including new candidates as well as already used RIs. We obtained 20 RIs for gamma-ray emission nuclides, in which 18 RIs are different from target elements and can be chemically separated.

Research Products

• [Journal Article] Evaluation of Neutron Induced Reaction Cross Section on Rh Isotopes (2014)
  • Author(s): N.Iwamoto.
  • Journal Title: JAEA-Conf (Japan Atomic Energy Agency) Volume: (投稿中)
• [Journal Article] First Measurement of the Radionuclide Purity of the Therapeutic Isotope ^67Cu Produced by ^<68>Zn(n,x) Reaction Using ^<na>tC(d,n) Neutrons (2014)
  • Author(s): N.Sato, K.Tsukada, S.Watanabe, N.S.Ishioka, M.Kawabata, H.Saeki, Y. Nagai, T.Kin, F.Minato, N.Iwamoto, O.Iwamoto.
  • Journal Title: Journal of the Physical Society of Japan Volume: 83(投稿中)
• [Journal Article] Generation of Radioisotopes with Accelerator Neutrons by Deuterons (2013)
  • Author(s): Y.Nagai, K.Hashimoto, Y.Hatsukawa, H. Saeki, S.Motoishi, N.Sato, M.Kawabata, H.Harada, T.Kin, K.Tsukada, T.K.Sato, F.Minato, O.Iwamoto, N.Iwamoto (他12名)
  • Journal Title: Journal of the Physical Society of Japan Volume: 82 Issue: 6 Pages: 064201-064201
  • DOI: 10.7566/jpsj.82.064201
  • NAID: 210000132593
• [Journal Article] Evaluation of Neutron Induced Reaction Cross Sections on Re Isotopes (2013)
  • Author(s): N.Iwamoto.
  • Journal Title: JAEA-Conf 2013-002 (Japan Atomic Energy Agency) Pages: 143-148
  • URL: http://jolissrch-inter.tokai-sc.jaea.go.jp/pdfdata/JAEA-Conf-2013-002.pdf
• [Journal Article] New Production Routes for Medical Isotopes 64Cu and 67Cu Using Accelerator Neutrons (2013)
  • Author(s): Tadahiro KIN
  • Journal Title: Journal of the Physical Society of Japan Volume: 82 Issue: 3 Pages: 034201-034201
  • DOI: 10.7566/jpsj.82.034201
  • Peer Reviewed
• [Journal Article] Evaluation of Neutron Induced Reaction Cross Sections on Re Isotopes (2013)
  • Author(s): N. Iwamoto
  • Journal Title: JAEA-Conf (Japan Atomic Energy Agency) Volume: -
  • Peer Reviewed
• [Presentation] Evaluation of Neutron Induced Reaction Cross Section on Rh Isotopes (2013)
  • Author(s): N.Iwamoto.
  • Organizer: 2013年度核データ研究会
  • Place of Presentation: 福井大学附属国際原子力工学研究所(福井県)
  • Year and Date: 2013-11-14
• [Presentation] バリウム同位体の中性子核データ評価 (2013)
  • Author(s): 岩本信之、柳田祥太郎
  • Organizer: 日本原子力学会2013年秋の大会
  • Place of Presentation: 八戸工業大学(青森県)
  • Year and Date: 2013-09-03
• [Presentation] Evaluation of Neutron Induced Reaction Cross Sections on Re Isotopes (2012)
  • Author(s): 岩本信之
  • Organizer: 2012年度核データ研究会
  • Place of Presentation: 京都大学原子炉実験所(大阪府)
  • Year and Date: 2012-11-15
• [Presentation] イリジウム同位体の核データ評価 (2012)
  • Author(s): 岩本信之
  • Organizer: 日本原子力学会2012年秋の大会
  • Place of Presentation: 広島大学東広島キャンパス(広島県)
  • Year and Date: 2012-09-20
• [Presentation] テクネチウム99の核データ評価 (2011)
  • Author(s): 岩本信之
  • Organizer: 日本原子力学会2011年秋の大会
  • Place of Presentation: 北九州国際会議場(福岡県)
  • Year and Date: 2011-09-21
• [Presentation] テクネチウム99の核データ評価 (2011)
  • Author(s): 岩本信之
  • Organizer: 日本原子力学会2011年秋の大会
  • Place of Presentation: 北九州国際会議場（福岡県）
• [Presentation] バリウム同位体の中性子核データ評価
  • Author(s): 岩本信之、柳田祥太郎
  • Organizer: 日本原子力学会 2013年秋の大会
  • Place of Presentation: 八戸工業大学（青森県）
• [Presentation] Evaluation of Neutron Induced Reaction Cross Sections on Rh Isotopes
  • Author(s): N.Iwamoto
  • Organizer: 2013年度核データ研究会
  • Place of Presentation: 福井大学附属国際原子力工学研究所（福井県）
• [Presentation] イリジウム同位体の核データ評価
  • Author(s): 岩本信之
  • Organizer: 日本原子力学会2012年秋の大会
  • Place of Presentation: 広島大学東広島キャンパス（広島県）
• [Presentation] Evaluation of Neutron Induced Reaction Cross Sections on Re Isotopes
  • Author(s): 岩本信之
  • Organizer: 2012年度核データ研究会
  • Place of Presentation: 京都大学原子炉実験所（大阪府）
• [Remarks] Y.Nagai, K.Hashimoto et al.、Generation of Radioisotopes with Accelerator Neutrons by Deuterons、Journal of the Physical Society of Japan、82、2013、064201(1-7)はJournal of the Physical Society of JapanのPapers of Editors'Choiceに選ばれた。