| Project/Area Number |
23602018
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical Physics/Radiological Technology
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| Research Institution | Kanagawa Cancer Center Research Institute |
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Principal Investigator |
MINOHARA Shinichi 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他 (60239332)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Naoyoshi 放射線医学総合研究所, 重粒子医科学センター, 室長 (90300912)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 仮想内視鏡 / 治療計画線量分布 / 放射線治療 / 重粒子線治療 / 肺門近接型肺がん |
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| Research Abstract |
In the clinical evaluation of lung cancer for radiotherapy, fiber-optic bronchoscopy is a crucial tool in the diagnosis of the tumor region before the treatment and in the evaluation of dose responses on tumor and normal tissues after the treatment. The conventional display for planning dose distribution is multi-planner reconstruction system, so it is so complex to correlate the dose distribution with the bronchoscopic image. To estimate effects of irradiation on lung tumor around bronchi, we have developed the unique visualizing system of planning dose distribution on virtual bronchoscopic images.
Clinical evaluation by this system was performed clinical cases of lung cancer treated with carbon-ion radiotherapy. The validity of the planned dose distribution has been checked from tissue responses such as tumor disappearance and bronchial obstruction after irradiation.
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