| Project/Area Number |
23617014
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrated Nutrition Science
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| Research Institution | University of Shizuoka |
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Principal Investigator |
UNNO Keiko 静岡県立大学, 薬学部, 准教授 (10106437)
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| Co-Investigator(Kenkyū-buntansha) |
SUGIURA Minoru 農業生物系特定産業技術研究機構, 果樹研究所, 主任研究官 (10355406)
KONISHI Tomokazu 秋田県立大学, 生物資源科学部, 准教授 (00281650)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 脳 / 老化 / 酸化ストレス / 社会心理ストレス / 社会心理的ストレス |
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| Research Abstract |
Catechins in green tea and beta-cryptoxanthin in Japanese mandarin orange suppressed senescence and age-related brain dysfunction in aged mice. The effective dose of these components suggests that green tea catechin and beta-cryptoxanthin prevent age-related brain dysfunction in human. Although accumulation of psychosocial stress accelerated brain senescence in mice, theanine, an amino acid in tea, suppressed stress-related brain dysfunction. Theanine had significant anti-stress effect in university students during pharmacy practice, suggesting that theanine prevents stress-related brain dysfunction in human.
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