Elucidation of the contribution of lymphatic transport to the intestinal absorption of various food factors
| Project/Area Number |
23617032
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrated Nutrition Science
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| Research Institution | Kinki University |
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Principal Investigator |
MUROTA Kaeko 近畿大学, 理工学部, 講師 (40294681)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKAHASHI Nobuyuki 京都大学, 大学院農学研究科, 助教 (50370135)
MURAKAMI Megumi 同志社女子大学, 生活科学部, 准教授 (80340769)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 腸管吸収 / リンパ系輸送 / カイロミクロン / フラボノイド / ビタミンE / プロビタミンAカロテノイド / リンパ輸送 / ヘスペレチン / プロビタミンA / ナノ粒子 / メチル水銀 / ケルセチン配糖体 / Caco-2 / CD36 |
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| Research Abstract |
We investigated the contribution of lymphatic transport to the intestinal absorption of various food factors, including vitamin E, carotenoids and flavonoids. Lymphatic transport level of highly hydrophobic vitamins was effectively enhanced when they were solubilized in the intestinal fluid, whereas a quercetin glucoside, a major flavonoid glycoside, was less absorbed when administrated with fatty acids simultaneously. It was also suggested that a relatively hydrophobic methoxyflavonoid was transported in the lymph at the higher level than quercetin.
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Report
(4 results)
Research Products
(7 results)
