• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Complehensive search of lifespan-regulating genes via metabolism

Research Project

Project/Area Number 23617033
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Integrated Nutrition Science
Research InstitutionJin-ai University (2014)
Kobe Gakuin University (2011-2013)

Principal Investigator

AMAKO Katsumi  仁愛大学, 人間生活学部, 准教授 (90275280)

Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords寿命 / 活性酸素 / 遺伝子 / アスコルビン酸 / ビタミンC / 酵母 / 老化 / 抗酸化物質 / 酸化ストレス / 代謝
Outline of Final Research Achievements

Disruption of cytosolic superoxide dismutase in budding yeast leads decrase in growth rate, oxidative stress resistance, and chloronological lifespan. L-Galactose and D-arabinose make budding yeast accumlate ascorbate and erythroascorbate, and they partically complemented the phenotypes in superoxide dismutase disruption mutant. In addition, the complementation by direct addition of ascorbate to yeast liquid culture was accomplished with different manner to L-galactose and D-arabinose.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (2 results)

All 2015 2012

All Presentation (2 results)

  • [Presentation] 細胞質CuZn-SOD欠損株における 酸化ストレス耐性および経時的寿命の 低下と、それらのアスコルビン酸・ エリスロアスコルビン酸による回復2015

    • Author(s)
      尼子克己
    • Organizer
      ビタミンC研究委員会
    • Place of Presentation
      お茶の水女子大学
    • Year and Date
      2015-03-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] 出芽酵母のsod1欠損による酸化ストレス・増殖・寿命への影響とそのアスコルビン酸による回復2012

    • Author(s)
      尼子克己、河野菜美、小野坂敏見、山西浩
    • Organizer
      日本栄養・食糧学会近畿支部大会
    • Place of Presentation
      甲子園大学
    • Related Report
      2012 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi