Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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Outline of Final Research Achievements |
Disruption of cytosolic superoxide dismutase in budding yeast leads decrase in growth rate, oxidative stress resistance, and chloronological lifespan. L-Galactose and D-arabinose make budding yeast accumlate ascorbate and erythroascorbate, and they partically complemented the phenotypes in superoxide dismutase disruption mutant. In addition, the complementation by direct addition of ascorbate to yeast liquid culture was accomplished with different manner to L-galactose and D-arabinose.
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