| Project/Area Number |
23650236
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory animal science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
CHIHIRO Koshimoto 宮崎大学, フロンティア科学実験総合センター, 教授 (70295210)
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| Co-Investigator(Kenkyū-buntansha) |
EDASHIGE Keisuke 高知大学, 教育研究部, 教授 (30175228)
MORITA Tetsuo 宮崎大学, 農学部, 教授 (90301382)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 実験動物学 / バイオリソース / Apodemus speciosus / Apodemus sylvaticus / 脂質異常症（高コレステロール血症） / 生殖工学 / ゲノム科学 / 高コレステロール血症 / Apodemus speciosu / 実験動物 / 高脂血症 |
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| Research Abstract |
In order to develop a new research resource which complements the existing lab-animals such as mice and rats, breeding stock construction and property evaluation in genus Apodemus which include Japanese endemic species have been started. The research performed in Japanese endemic species (A. speciosus) and the European species (A. sylvaticus) as main targets. In the former, the world's first breeding colony has been constructed under indoor condition and fundamental technique development relating to embryo handling in vitro has been started. In the latter which can maintain indoor, it has become clearer that their hyperlipemia characteristic is corresponding to that in human but in mouse or rat. These results indicate that Apodemus could have a high potential as a unique bio-resource.
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