Development of antibody recognition imaging method for cancer diagnosis
Project/Area Number |
23650271
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Keio University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
TABATA Noriko 慶應義塾大学, 理工学研究科, 特任准教授 (60260080)
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Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | iPS細胞 / がん幹細胞 / in vitro virus法 / CD44 / in vivo imaging / CD138 |
Research Abstract |
Since CD44 is considered to be one of the factors required in order to maintain the autonomous replication ability of cancer stem cells as adhesion molecules, we performed to select single strand antibodies which prevent the induced cancer stem
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Report
(3 results)
Research Products
(17 results)
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[Journal Article] A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma2012
Author(s)
Shiheido, H., Terada, F., Tabata, N., Hayakawa, I., Matsumura, N., Takashima, H., Ogawa, Y., Du,W., Yamada, T., Shoji, M., Sugai, T., Doi, N.,Iijima, S., Hattori, Y., Yanagawa, H.
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Journal Title
PLoS ONE
Volume: 7
Issue: 6
Pages: e38878-e38878
DOI
Related Report
Peer Reviewed
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[Journal Article] DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells2011
Author(s)
Doi,N.,Yamakawa,N.,Matsumoto,H.,Yamamoto,Y.,Nagano,T.,Matsumura,N.,Horisawa,K.,Yanagawa,H.
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Journal Title
PLoS ONE
Volume: 7
Issue: 1
Pages: 1-8
DOI
Related Report
Peer Reviewed
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[Presentation] In vitroevolution of high-affinity anti-CCR5 single chain Fv via neutral drift libraries2011
Author(s)
Sato, R., Doi,N., Misumi,S., Shoji,S., Matsushima, S., Yokochi, S., Yanagawa, H.
Organizer
34th MBSJ 2011
Place of Presentation
Yokohama
Year and Date
2011-12-13
Related Report
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[Presentation] In vitroselection of anti-CD44v scFv inhibiting CD44v-xCT interaction2011
Author(s)
Umezawa,H., Tabata,N., Sakuma,Y., Takenaka,Y., Matsumoto,Y., Doi,N., Nagano, O., Saya,H., Yanagawa, H.
Organizer
34th MBSJ 2011
Place of Presentation
Yokohama
Year and Date
2011-12-13
Related Report
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[Presentation] In vitroselection of Fc receptor-binding peptides using in vitro virus method2011
Author(s)
Mihara, M., Sumida, T., Sakuma, Y., Tabata, N., Horisawa, K., Yanagawa, H., Doi, N.
Organizer
34th MBSJ 2011
Place of Presentation
Yokohama
Year and Date
2011-12-11
Related Report
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[Presentation] Selection of scFv inhibiting adhesion of induced cancer stem cells by in vitro virus (IVV) method2011
Author(s)
Tabata, N., Sakuma, Y., Shimizu, T., Saya, H., Doi, N., Yanagawa, H.
Organizer
34th MBSJ 2011
Place of Presentation
Yokohama
Year and Date
2011-12-11
Related Report
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[Book] Chemical Synthetic Biology2011
Author(s)
Nobuhide Doi, Koichi Kakukawa, Yo Oishi, and Hiroshi Yanagawa
Total Pages
8
Publisher
High solubility of random-sequence proteins consisting of five kinds of primitive amino acids
Related Report
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