Acquired Disease Treatment by Epigenetics Engineering
| Project/Area Number |
23650291
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | エピジェネティクス / DNA メチル化 / ヒストン修飾 / クロマチン / DNAメチル化 / 高分子 |
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| Research Abstract |
In this reserach, to establish epigenetics engineering for cellular differentiation, we have designed new biodegradable nanospheres for controlled release. A prepared new carrier was delivered into human leukemia HL-60 cells, resulting in significant differentiation to granulocytic cells.
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Report
(3 results)
Research Products
(6 results)
