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Development of Sono-cytometry by High Frequency Ultrasound

Research Project

Project/Area Number 23650300
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical systems
Research InstitutionTohoku University

Principal Investigator

SAIJO Yoshifumi  東北大学, 大学院・医工学研究科, 教授 (00292277)

Co-Investigator(Kenkyū-buntansha) KANAI Hiroshi  東北大学, 大学院・工学研究科, 教授 (10185895)
HAYASE Toshiyuki  東北大学, 流体科学研究所, 教授 (30135313)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords高周波数超音波 / サイトメトリー / マイクロ流路 / ニューラルネットワーク
Research Abstract

Microfluidic circulation with suspension of micro-molecules was observed by high speed CCD camera. High frequency ultrasound of 120 MHz was emitted to the model and the spectrum of the reflected ultrasound was analyzed by neural network. The dimensions and structures of the micro-molecules were evaluated by the method. Application of the blood flow or lymph flow to the method in living subjects may realize in vivo “sono-cytometry" in the near future.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (30 results)

All 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (14 results) (of which Invited: 3 results) Book (6 results) Remarks (3 results)

  • [Journal Article] High-resolution ultrasound imaging of human skin in vivo by using three-dimensional ultrasound microscopy2012

    • Author(s)
      Kumagai K, Koike H, Nagaoka R, Sakai S, Kobayashi K, Saijo Y
    • Journal Title

      Ultrasound Med Biol

      Volume: Vol. 38, No. 10 Issue: 10 Pages: 1833-8

    • DOI

      10.1016/j.ultrasmedbio.2012.05.012

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Coexistence of fibrotic and chondrogenic process in the capsule of idiopathic frozen shoulders2012

    • Author(s)
      Hagiwara Y, Ando A, Onoda Y, Takemura T, Minowa T, Hanagata N, Tsuchiya M, Watanabe T, Chimoto E, Suda H, Takahashi N, Sugaya H, Saijo Y, Itoi E
    • Journal Title

      Osteoarthritis Cartilage

      Volume: Vol. 20, No. 3 Issue: 3 Pages: 241-9

    • DOI

      10.1016/j.joca.2011.12.008

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of articular cartilage images assessed by high-frequency ultrasound microscope and scanning acoustic microscope2012

    • Author(s)
      Hagiwara Y, Saijo Y, Ando A, Onoda Y, Suda H, Chimoto E, Hatori K, Itoi E
    • Journal Title

      Int Orthop

      Volume: Vol. 6, No. 1 Issue: 1 Pages: 185-90

    • DOI

      10.1007/s00264-011-1263-1

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Echogenicity in transrectal ultrasound is determined by sound speed of prostate tissue components2012

    • Author(s)
      Tanoue H, Hagiwara Y, Kobayashi K, Saijo Y
    • Journal Title

      Conf Proc 34th IEEE Eng Med Biol Soc

      Volume: 1 Pages: 460-463

    • DOI

      10.1109/embc.2012.6345967

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of vortex flow in left ventricle by echo-dynamography and phase contrast magnetic resonance angiography2012

    • Author(s)
      Kojima T, Kameyama T, Nakajima H, Khmyrova E, Kurokawa T, Saijo Y
    • Journal Title

      Conf Proc 34th IEEE Eng Med Biol Soc

      Volume: 1 Pages: 2676-2679

    • DOI

      10.1109/embc.2012.6346515

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imaging of sebaceous glands of human skin by three-dimensional ultrasound microscopy and its relation to elasticity2011

    • Author(s)
      Kumagai K, Koike H, Kudo Y, Nagaoka R, Kubo K, Kobayashi K, Saijo Y
    • Journal Title

      Conf Proc 33rd IEEE Eng Med Biol Soc

      Volume: 1 Pages: 7199-7202

    • DOI

      10.1109/iembs.2011.6091819

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Ultrasonic tissue characterization of prostate biopsy tissues by ultrasound speed microscope2011

    • Author(s)
      Tanoue H, Hagiwara Y, Kobayashi K, Saijo Y
    • Journal Title

      Conf Proc 33rd IEEE Eng Med Biol Soc

      Volume: 1 Pages: 8499-8402

    • DOI

      10.1109/iembs.2011.6092097

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Feasibility of echo-dynamography in comparison of blood flow vectors obtained fromechocardiography and phase contrast magnetic resonance angiography2013

    • Author(s)
      Saijo Y, Kojima T, Khmyrova E, Omori A, Nakajima H, Kurokawa T, Tabuchi H, Kameyama T, Tanaka M.
    • Organizer
      Asian Pacific Society of Cardiology2013 Congress (19th APCC or APSC2013)
    • Place of Presentation
      Pattaya, Thailand
    • Related Report
      2012 Final Research Report
  • [Presentation] Feasibility of echo-dynamography in comparison of blood flow vectors obtained from echocardiography and phase contrast magnetic resonance angiography2013

    • Author(s)
      Saijo Y, Kojima T, Khmyrova E, Omori A, Nakajima H, Kurokawa T, Tabuchi H, Kameyama T, Tanaka M
    • Organizer
      Asian Pacific Society of Cardiology 2013 Congress
    • Place of Presentation
      Pattaya, Thailand
    • Related Report
      2012 Annual Research Report
  • [Presentation] 超音波ドプラデータに基づく心臓内渦流の可視化2012

    • Author(s)
      小島貴則,中島博行,黒川貴史,大森愛子,西條芳文
    • Organizer
      第15回日本栓子検出と治療学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 細動脈を模擬した生体ファントムの作製2012

    • Author(s)
      小松洋介,長岡亮,太田信,船本健一,早瀬敏幸,金井浩,西條芳文
    • Organizer
      第15回日本栓子検出と治療学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] Application of acoustic microscopy for prostate biopsy tissues. Key Note Lecture2012

    • Author(s)
      Saijo Y.
    • Organizer
      8th International Symposium on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      St- Paulin, Quebec, Canada
    • Related Report
      2012 Final Research Report
  • [Presentation] 心エコーとMRIのハイブリッドイメージングによる左室内渦流の三次元評価2012

    • Author(s)
      西條芳文,小島貴則,亀山剛義,中島博行,田渕晴名,田中元直
    • Organizer
      第60回日本心臓病学会学術集会
    • Place of Presentation
      金沢
    • Related Report
      2012 Final Research Report
  • [Presentation] Recent development on biomedical acoustic microscopy2012

    • Author(s)
      Saijo Y.
    • Organizer
      International Conference on Sensing, Imaging and Signal Processing
    • Place of Presentation
      Santa Barbara, CA, USA.
    • Related Report
      2012 Final Research Report
  • [Presentation] High resolution biomedical imaging - Multimodal ultrasound microscope and combination with optics2012

    • Author(s)
      Saijo Y.
    • Organizer
      Invited Paper in The Acoustics2012 Hong Kong conference consisting a joint meeting of the 163rd meeting of the Acoustical Society of America (ASA), the 8th meeting of the Acoustical Society of China (ASC), the 11th Western Pacific Acoustics Conference (WESPAC) and the Hong Kong Institute of Acoustics (HKIOA) organized by the Hong Kong Institute of Acoustics
    • Place of Presentation
      Hong Kong, China
    • Related Report
      2012 Final Research Report
  • [Presentation] Evaluation of tissue components, biomechanics and blood flow by high frequency ultrasound2012

    • Author(s)
      Saijo Y.
    • Organizer
      Invited Lecture in American Institute of Ultrasound in Medicine (AIUM)2012 Annual Convention
    • Place of Presentation
      Phoenix, AZ, USA.
    • Related Report
      2012 Final Research Report
  • [Presentation] High resolution biomedical imaging - Multimodal ultrasound microscope and combination with optics2012

    • Author(s)
      Saijo Y
    • Organizer
      The Acoustics 2012 Hong Kong conference consisting a joint meeting of the 163rd meeting of the Acoustical Society of America (ASA)
    • Place of Presentation
      Hong Kong, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Application of acoustic microscopy for prostate biopsy tissues2012

    • Author(s)
      Saijo Y
    • Organizer
      8th International Symposium on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      St-Paulin, Quebec, Canada
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Recent development on biomedical acoustic microscopy2012

    • Author(s)
      Saijo Y
    • Organizer
      International Conference on Sensing, Imaging and Signal Processing
    • Place of Presentation
      Santa Barbara, CA, USA
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Evaluation of tissue components, biomechanics and blood flow by high frequency ultrasound.2012

    • Author(s)
      Saijo Y
    • Organizer
      2012 AIUM Annual Convention(招待講演)
    • Place of Presentation
      Phoenix, AZ, USA
    • Related Report
      2011 Research-status Report
  • [Presentation] IVUS is still alive.2011

    • Author(s)
      Saijo Y
    • Organizer
      2011 IEEE International Ultrasonics Symposium(招待講演)
    • Place of Presentation
      Orlando, MI, USA
    • Related Report
      2011 Research-status Report
  • [Book] Color dependence of photoacoustic micro imaging. Andrzej Nowicki, Jerzy Litniewski, Tamara Kujawska eds2012

    • Author(s)
      Saijo Y, Koike H, Izumi T, Miida Y, Matsuura Y, Hozumi N
    • Publisher
      Acoustical Imaging Vol 31, Springer
    • Related Report
      2012 Final Research Report
  • [Book] Tribikram Kundu ed. Ultrasonic and Electromagnetic NDE for Structure and Material Characterization: Engineering and Biomedical Applications CRC Press2012

    • Author(s)
      Saijo Y.
    • Publisher
      Clinical applications of ultrasonic nondestructive evaluation
    • Related Report
      2012 Final Research Report
  • [Book] Technological Advancements in Biomedicine for Healthcare Applications, IGI Global2012

    • Author(s)
      Saijo Y.
    • Publisher
      Biomedical application of multimodal ultrasound microscope.Jinlong Wu ed
    • Related Report
      2012 Final Research Report
  • [Book] Acoustical Imaging2012

    • Author(s)
      Saijo Y, Koike H, Izumi T, Miida Y, Matsuura Y, Hozumi N
    • Publisher
      Color dependence of photoacoustic micro imaging
    • Related Report
      2012 Annual Research Report
  • [Book] Ultrasonic and Electromagnetic NDE for Structure and Material Characterization: Engineering and Biomedical Applications2012

    • Author(s)
      Saijo Y
    • Publisher
      Clinical applications of ultrasonic nondestructive evaluation
    • Related Report
      2012 Annual Research Report
  • [Book] Technological Advancements in Biomedicine for Healthcare Applications2012

    • Author(s)
      Saijo Y
    • Publisher
      Biomedical application of multimodal ultrasound microscope
    • Related Report
      2012 Annual Research Report
  • [Remarks] 西條研究室

    • URL

      http://www.ecei.tohoku.ac.jp/imaging/

    • Related Report
      2012 Final Research Report
  • [Remarks] 西條研究室

    • URL

      http://www.ecei.tohoku.ac.jp/imaging/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.ecei.tohoku.ac.jp/imaging/

    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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