Molecular basis of epigenetic regulation by ultrasound
| Project/Area Number |
23650303
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical systems
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| Research Institution | University of Toyama |
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Principal Investigator |
TABUCHI Yoshiaki 富山大学, 生命科学先端研究センター, 准教授 (20322109)
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| Co-Investigator(Kenkyū-buntansha) |
KONDO Takashi 富山大学, 大学院・医学薬学研究部 (医学), 教授 (40143937)
WADA Shigehito 富山大学, 大学病院, 講師 (50303219)
IKEGAME Mika 岡山大学, 医歯(薬)学総合研究科, 准教授 (70282986)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 超音波 |
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| Research Abstract |
Low-intensity pulsed ultrasound (LIPUS) has been used extensively as an adjuvant to fracture healing. We identified many up-regulated genes that were associated with bone morphology in mouse osteoblast cells treated with a single 20-min LIPUS (1.5 MHz, 30 mW/cm2) using global-scale gene expression analyzing technologies. These results obtained here should help to further clarify the molecular basis of the mechanisms of the LIPUS response in osteoblast cells.
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Report
(4 results)
Research Products
(13 results)
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[Journal Article] Development of Oral Epithelial Cell Line ROE2 with Differentiation Potential from Transgenic Rats Harboring Temperature-Sensitive Simian Virus40 Large T-Antigen Gene2014
Author(s)
Tabuchi Y, Wada S, Ikegame M, Kariya A, Furusawa Y, Hoshi N, Yunoki T, Suzuki N, Takasaki I, Kondo T, Suzuki Y
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Journal Title
Experimental Animals
Volume: 63
Issue: 1
Pages: 31-44
DOI
NAID
ISSN
0007-5124, 1341-1357, 1881-7122
Related Report
Peer Reviewed / Open Access
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