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Ultra-rapid defrosting techniques of cryopreserved tissues and organs

Research Project

Project/Area Number 23650305
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical systems
Research InstitutionUniversity of Toyama

Principal Investigator

NAKAMURA Makoto  富山大学, 大学院・理工学研究部(工学), 教授 (90301803)

Co-Investigator(Renkei-kenkyūsha) IWANAGA Shintaroh  東京大学, 生産技術研究所, 研究員 (70587972)
TODA Hideki  富山大学, 大学院・理工学研究部(工学), 講師 (10520687)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords臓器保存 / 再生組織 / 凍結保存 / 解凍 / 人工赤血球 / 冷凍保存 / 組織保存 / クライオバイオロジー / 電磁誘導 / 凍結傷害 / 解凍過程
Research Abstract

The necessity for the technologies of cryopreservation of living tissues and organs is increasing. We have not yet effective means for cryopreservation of tissue and organ especially for the defrosting process, where the cryo-injury process advances both duringfreezing process and during thawing processes. Then, we devised and challenged to develop an ultra-rapid defrosting technique, in which tissues can be defrosted extremely rapidlyfrom the inside of the blood vessels by electro-magnetic induction. In this study, the electromagnetic induction heating cookers were converted and the production of the artificial red blood cell which generates heat by electromagnetic induction was challenged.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (17 results)

All 2013 2012 2011 Other

All Journal Article (1 results) Presentation (16 results) (of which Invited: 1 results)

  • [Journal Article] Facile fabrication of uniform size-controlled microparticles and potentiality for tandem drug delivery system of micro/nanoparticles.2013

    • Author(s)
      Iwanaga S, Saito N, Sanae H, Nakamura M.
    • Journal Title

      Colloids Surf B Biointerfaces

      Volume: 19 Pages: 301-306

    • Related Report
      2012 Final Research Report
  • [Presentation] 未来を担う再生医療・組織工学最前線; 「組織工学のためのバイオマテリアルの進歩と実用化への期待」2012

    • Author(s)
      中村真人,竹田朋恵、早苗秀敏、荒井健一,岩永進太郎
    • Organizer
      日本バイオマテリアル学会シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2012-11-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 細胞組み込み型ヒト人工組織の3次元に向けた戦略2012

    • Author(s)
      中村真人
    • Organizer
      第11回日本再生医療学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 赤血球サイズのヘモグロビン含有マイクロゲルビーズの作製2012

    • Author(s)
      竹田朋恵、齊藤典彰、岩永進太郎、中村真人
    • Organizer
      第11回 日本再生医療学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Production of hemoglobin-containing micro-gel beads as oxygen carriers for cell culture TERMIS World congress2012

    • Author(s)
      T. Takeda, S. Iwanaga, N. Saitou, M.Nakamura
    • Organizer
      Wien, Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] ヘモグロビン含有アルギン酸ゲルビーズの作製:培養用酸素運搬体としての評価2012

    • Author(s)
      竹田朋恵、岩永進太郎、齊藤典彰、中村真人
    • Organizer
      第一回日本バイオマテリアル 学会 北陸若手研究発表会
    • Place of Presentation
      金沢
    • Related Report
      2012 Final Research Report
  • [Presentation] 赤血球サイズのヘモグロビン含有マイクロゲルビーズの作製、2012

    • Author(s)
      竹田朋恵、齊藤典彰、岩永進太郎、中村真人、
    • Organizer
      第11回 日本再生医療学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] Production of hemoglobin-containing micro-gel beads as oxygen carriers for cell culture2012

    • Author(s)
      Tomoe Takeda, Shintaroh Iwanaga, Noriaki Saitou, Makot Nakamura.
    • Organizer
      TERMIS World congress,
    • Place of Presentation
      ウィーン、オーストリア
    • Related Report
      2012 Annual Research Report
  • [Presentation] 培養用人工酸素運搬体としてのヘモグロビンゲルビーズの作製2011

    • Author(s)
      竹田朋恵,齊藤典彰,岩永進太郎,中村真人
    • Organizer
      生体医工学会第50回日本生体医工学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] インクジェット技術による微粒子の作製2011

    • Author(s)
      竹田朋恵、齊藤典彰、岩永進太郎、中村真人
    • Organizer
      富山大学コラボフェスタ2011新技術紹介ポスター発表会
    • Place of Presentation
      富山
    • Related Report
      2012 Final Research Report
  • [Presentation] インクジェット再生医工学:培養用ヘモグロビンゲルビーズの作製2011

    • Author(s)
      竹田朋恵、齊藤典彰、岩永進太郎、中村真人
    • Organizer
      第49回日本人工臓器学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 培養用ヘモグロビン含有ゲルビーズの作製2011

    • Author(s)
      竹田朋恵 齊藤典彰 岩永進太郎 中村真人
    • Organizer
      平成23年度生体医工学会北陸支部大会
    • Place of Presentation
      金沢(研究奨励賞受賞)
    • Related Report
      2012 Final Research Report
  • [Presentation] M.Nakamura Cryopreservation of bio-fabricated 3D bio-constructs: Visualization of the freezing process of cell embedded hydrogel structures2011

    • Author(s)
      Y. Yoneda, H. Toda, S. Iwanaga, H.Teranishi
    • Organizer
      2nd international conference of international society for Biofabrication
    • Place of Presentation
      Biofabrication 2011 in Toyama
    • Related Report
      2012 Final Research Report
  • [Presentation] 組織・臓器の凍結保存の研究2011

    • Author(s)
      米田裕香、奈須野雅明、戸田英樹、寺西葉月、岩永進太郎、中村真人
    • Organizer
      日本バイオマテリアル学会北陸若手研究者発表会
    • Place of Presentation
      福井
    • Related Report
      2012 Final Research Report 2011 Research-status Report
  • [Presentation] Cryopreservation of bio-fabricated 3D bio-constructs: Visualization of the freezing process of cell embedded hydrogel structures,2011

    • Author(s)
      Yuka Yoneda, Hideki Toda, Shintaroh Iwanaga, Hazuki Teranishi, Makoto Nakamura .
    • Organizer
      2nd international conference of international society for Biofabrication, Biofabrication 2011 in Toyama,
    • Place of Presentation
      Toyama, Japan
    • Related Report
      2011 Research-status Report
  • [Presentation] ヘモグロビン含有アルギン酸ゲルビーズの作製:培養用酸素運搬体としての評価

    • Author(s)
      竹田朋恵、岩永進太朗、齊藤典彰、中村真人
    • Organizer
      第一回日本バイオマテリアル 学会 北陸若手研究発表会、
    • Place of Presentation
      金沢
    • Related Report
      2012 Annual Research Report
  • [Presentation] 細胞組み込み型ヒト人工組織の3次元に向けた戦略.

    • Author(s)
      中村真人、
    • Organizer
      第11回日本再生医療学会総会 ランチョンセミナー講演
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
    • Invited

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Published: 2011-08-05   Modified: 2019-07-29  

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