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A suppression and separation method of the water solvent signal for the improvement of the accuracy and stability in noninvasive blood glucose measurement

Research Project

Project/Area Number 23650311
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Medical systems
Research InstitutionMeiji University

Principal Investigator

ISHIHARA Yasutoshi  明治大学, 理工学部, 教授 (00377219)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords検査 / 診断システム / 検査・診断システム / 血糖値 / 非侵襲 / グルコース / 光 / 計測工学 / 光物性 / 光音響 / PAS / 分光 / 糖尿病
Research Abstract

In a noninvasive blood glucose measurement based on a near infrared light, it is necessary to suppress the signal of the water solvent, which is the main causes of background noise, to improve the accuracy and stability of measurement. In this research, we proposed the method of measuring a glucose signal, irradiating a sample with the excitation light that has a wavelength corresponding to the maximum absorption of the water molecule. It was shown that the signal originated from the water molecule could be separated effectively, as a result of the fundamental experiment. Furthermore, it was shown clearly that glucose concentration could be estimated by about 10% of precision for measurement based on this method.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (7 results)

All 2013 2011 Other

All Presentation (4 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Presentation] 光音響分光法を用いた生体情報計測プローブの小型化・高感度化に関する研究2011

    • Author(s)
      楊振謖、浅野達彦、石原康利、和田森直、
    • Organizer
      生体医工学シンポジウム2011
    • Place of Presentation
      長野市
    • Year and Date
      2011-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 光音響分光法における生体情報計測用I字型セルの解析2011

    • Author(s)
      浅野達彦、楊振謖、石原康利、和田森直
    • Organizer
      生体医工学シンポジウム2011
    • Place of Presentation
      長野市
    • Year and Date
      2011-09-16
    • Related Report
      2012 Final Research Report 2011 Research-status Report
  • [Presentation] 非侵襲血糖値計測における背景雑音の抑制技術に関する研究

    • Author(s)
      楊振謖
    • Organizer
      生体医工学シンポジウム2012
    • Place of Presentation
      大阪市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 光音響分光法を用いた生体情報計測プローブの小型化・高感度化に関する研究

    • Author(s)
      楊振謖、浅野達彦、石原康利、和田森直
    • Organizer
      生体医工学シンポジウム2011
    • Place of Presentation
      長野市
    • Related Report
      2011 Research-status Report
  • [Remarks]

    • URL

      http://www.isc.meiji.ac.jp/~insteng/

    • Related Report
      2012 Final Research Report
  • [Remarks] 計測工学研究室(石原研) 明治大学理工学部

    • URL

      http://www.isc.meiji.ac.jp/~insteng/

    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] パラメータ計測装置、パラメータ計測方法、及びプログラム2013

    • Inventor(s)
      石原康利、石原康男、中村佳右
    • Industrial Property Rights Holder
      学校法人明治大学
    • Industrial Property Number
      2013-045981
    • Filing Date
      2013-03-07
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Overseas

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Published: 2011-08-05   Modified: 2019-07-29  

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