The evaluation of exercise effect in muscle atrophy by development of muscular strength measuring device for mice
| Project/Area Number |
23650339
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Rehabilitation science/Welfare engineering
|
|---|
| Research Institution | Nagoya Gakuin University |
|---|
Principal Investigator |
HIRANO Takayuki 名古屋学院大学, リハビリテーション学部, 教授 (10440661)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ITOH Yuta 名古屋学院大学, リハビリテーション学部, 助教 (30454383)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
|---|
| Keywords | 理学療法学 / 筋萎縮 / 筋力 / マウス / リハビリテーション科学 / 運動療法学 / 動物 / 骨・筋肉 / 筋肉生理学 |
|---|
| Research Abstract |
We developed the equipment which can noninvasively and sequentially measure the maximum Plantar-flexion torque of mouse, and investigated the relationship between histological effect and the functional effect of resistance exercise (RE) in facilitating recovery from the muscle atrophy. As a result, the histological effect from the muscle atrophy by RE was observed in the myofiber cross sectional area of the soleus muscle. However, the functional effect in plantar-flexion torque was not able to be observed, suggesting that the difference is due to the histological change of other plantar-flexior muscles were small. However, the torque change by muscle atrophy or its recovery process has been sequentially evaluated by using this equipment.
|
Report
(3 results)
Research Products
(8 results)
