| Project/Area Number |
23650406
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Sports science
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| Research Institution | The University of Tokushima |
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Principal Investigator |
IMOTO Issei (TACHIBANA Issei) 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (30258610)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAYA Yutaka 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (50136222)
NIKAWA Takeshi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (20263824)
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| Co-Investigator(Renkei-kenkyūsha) |
TAJIMA Atsushi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 (10396864)
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| Project Period (FY) |
2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Keywords | 高運動習性ラット / ゲノム / 次世代シーケンサー / 連鎖解析 |
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| Research Abstract |
In order to identify gene(s) and molecular pathway(s) possibly related to the phenotype of model rats with high levels of voluntarily wheel running activity(Spontaneously-Running-Tokushima-Shikoku, SPORTS) established from Wistar rats, we established a novel integrated screening system through combining exome sequencing using a next-generation sequencer, linkage analysis, and selection algorithm using genome and polymorphism databases. Through this study, we successfully established a novel screening system for rat genome analysis and identified a set of candidate genes related to the phenotype of SPORTS rats.
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