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Non-invasive, continuous measurement for intermediate metabolite and ion dynamics of skeletal muscle during muscle contraction

Research Project

Project/Area Number 23650408
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

KIMURA Misaka  京都府立医科大学, 医学部, 教授 (90150573)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords生体電気インピーダンス分光法 / 骨格筋 / 細胞内液 / 細胞外液 / 運動 / 生体電気インピーダンス法 / 代謝 / 部位別多周波インピーダンス(S-BIS)法 / 筋細胞内水分の連続測定
Research Abstract

The aim of this study is explore the possibility of using segmental multi-frequency bioelectrical impedance spectroscopy (S-BIS) to measure the dynamics of metabolism in human skeletal muscle. We examined the application of non-invasive measurement of water distribution using electrical property of cell membrane in skeletal muscle. During exercise, intra-cellular water rapidly increased and extra-cellular water decreased at the time of decreasing oxygenated hemoglobin in the tissue. From the results of several experiments, S-BIS has a possibility to detect the dynamics of metabolism in skeletal muscle during exercise.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (4 results)

All 2012 Other

All Presentation (2 results) Patent(Industrial Property Rights) (2 results)

  • [Presentation] Relationship between muscle strength and muscle volume estimates using segmental bioelectrical impedance spectroscopy in the elderly.2012

    • Author(s)
      Y Yamada, K Yokoyama, T Morimoto, M Kimura
    • Organizer
      International Conference on Sarcopenia Research
    • Place of Presentation
      Orlando, FL, USA
    • Year and Date
      2012-12-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Relationship between muscle strength and muscle volume estimates using segmental bioelectrical impedance spectroscopy in the elderly

    • Author(s)
      Y Yamada, K Yokoyama, T Morimoto, M Kimura
    • Organizer
      International Conference on Sarcopenia Research
    • Place of Presentation
      Orlando, FL, USA
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] 筋肉量測定方法及び筋肉量測定装2012

    • Inventor(s)
      山田陽介、木村みさか
    • Industrial Property Rights Holder
      山田陽介、木村みさか
    • Industrial Property Number
      2012-220087
    • Filing Date
      2012-10-02
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 筋肉量測定方法及び筋肉量測定装置2012

    • Inventor(s)
      山田陽介、木村みさか
    • Industrial Property Rights Holder
      山田陽介、木村みさか
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-220087
    • Filing Date
      2012
    • Related Report
      2012 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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