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Method to evaluate accurate response waveforms of cardiovascular system to external perturbations and its application to healthcare supports system

Research Project

Project/Area Number 23650415
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionThe University of Tokyo

Principal Investigator

KOTANI Kiyoshi  東京大学, 大学院・新領域創成科学研究科, 准教授 (00372409)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords生物・生体工学 / 循環器・高血圧 / 生理学 / ユーザインタフェース / 脳・神経 / ユーザインターフェイス / 心拍変動 / 呼吸位相 / 血圧
Research Abstract

It is important to evaluate the response of the cardiovascular system to external stimuli for understanding homeostasis. However, the response should be distorted by the conventional time domain analysis when a frequency of the effect of external stimuli matches that of intrinsic fluctuations. The purpose of this study is to propose a mixed signal processing of time domain and respiratory phase domain to extract the response waveforms of heartbeat and blood pressure (BP) to external stimuli and to clarify the reaction mechanisms of the cardiovascular system.
First, cardiovascular responses to swallowing are investigated. Sudden tachycardia and changes of blood pressure is accurately extracted and evaluated. Second, responses to postural changes investigated. It is confirmed that there is dispersion between systolic and diastolic blood pressure as their response waveforms. Third, application to detect startling is tested and the accuracy of the detection is improved using cardiovascular response.
In conclusion, the proposed method accurately evaluates response waveforms to external stimuli from the cardiovascular system in the time domain and enable for physiologicalconsiderations. The method would be applicable to several daily-life situations such as prevention of orthostatic syncope and startling detections.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (6 results)

All 2013 2012 2011 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Effect of body motion to respiratory sinus arrhythmia with different timings of respiration2013

    • Author(s)
      T. Numata, K. Kotani, Y. Jimbo
    • Journal Title

      International Journal of Bioelectromagnetism

      Volume: 15 Pages: 47-53

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Presentation] ニオイ刺激のバイオフィードバック応用に向けた脳・循環器応答の評価2012

    • Author(s)
      岸田悠志,沼田崇志,小川雄太郎,竹野翔兵,小谷潔,神保泰彦
    • Organizer
      平成24年電気学会電子・情報・システム部門大会
    • Place of Presentation
      弘前大学
    • Related Report
      2012 Final Research Report
  • [Presentation] ニオイ刺激のバイオフィードバック応用に向けた脳・循環器応答の評価2012

    • Author(s)
      岸田悠志,沼田崇志,小川雄太郎,竹野翔兵,小谷潔,神保泰彦
    • Organizer
      平成24年電気学会情報・システム部門大会
    • Place of Presentation
      弘前大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 体動および呼吸リズムが呼吸性洞性不整脈に与える影響の評価2011

    • Author(s)
      沼田崇志,小谷潔,神保泰彦
    • Organizer
      平成23年電気学会電子・情報・システム部門大会
    • Place of Presentation
      富山大学
    • Related Report
      2012 Final Research Report
  • [Presentation] 体動および呼吸リズムが呼吸性洞性不整脈に与える影響の評価2011

    • Author(s)
      沼田崇志,小谷潔,神保泰彦
    • Organizer
      平成23年電気学会電子・情報・システム部門大会
    • Place of Presentation
      富山大学五福キャンパス
    • Related Report
      2011 Research-status Report
  • [Remarks] なし

    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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