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Estimation of health status by exhaled gas analysis

Research Project

Project/Area Number 23650427
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionHirosaki University

Principal Investigator

NAKAJI Shigeyuki  弘前大学, 医学(系)研究科(研究院), 教授 (10192220)

Co-Investigator(Kenkyū-buntansha) MATSUZAKA Masashi  弘前大学, 大学院医学研究科, 講師 (70431434)
DANJO Kazuma  弘前大学, 大学院医学研究科, 助教 (90463760)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords呼気 / 水素 / メタン / 一酸化炭素 / 好中球機能 / 過敏性腸症候群 / ライフスタイル / 活性酸素 / 呼気ガス / 健康度 / 一般住民 / 加齢 / 岩木健康増進プロジェクト / いわき健康増進プロジェクト
Research Abstract

Following results were obtained from the investigation between exhaled gas, irritable bowel syndrome (IBS), neutrophil functions and lifestyles among 992 adults. 1. IBS group - significantly high level of exhaled hydrogen concentration was observed in females with IBS-D (IBS with diarrhea) compared with females in normal group, IBS with constipation or IBS with both diarrhea and constipation. 2. Negative correlations were observed between serum opsonic activity (Luminol-dependent chemiluminescence) and exhaled carbon monoxide in both genders. In addition, positive correlation was observed between serum opsonic activity (Lucigenin-dependent chemiluminescence) and exhaled carbon monoxide in females. 3. As for the association between exhaled carbon monoxide and age, BMI, the amount of alcohol consumption and exercise habit, no significant correlations were observed in any items. Therefore, certain relationships were found between exhaled gas and diseases, health status and lifestyle.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (13 results)

All 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (5 results) Remarks (1 results)

  • [Journal Article] The influence of blood glucose on neutrophil function in individuals without diabetes.2013

    • Author(s)
      Saito Y, Takahashi I, Iwane K, Okubo N, Nishimura M, Matsuzaka M, Wada N, Miwa T, Umeda T, Nakaji S. 2013
    • Journal Title

      Luminescence

      Volume: 28 Issue: 4 Pages: 569-573

    • DOI

      10.1002/bio.2495

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Serum hyaluronan levels increase with the total number of osteoarthritic joints and are strongly associated with the presence of knee and finger osteoarthritis2013

    • Author(s)
      Sasaki Eiji
    • Journal Title

      Int Orthop

      Volume: 37 Issue: 5 Pages: 925-30

    • DOI

      10.1007/s00264-013-1849-x

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Gender Differences in Factors Associated with Suicidal Ideation and Depressive Symptoms among Middle-Aged Workers in Japan.2013

    • Author(s)
      Sugawara N, Yasui-Furukori N, Sasaki G, Tanaka O, Umeda T, Takahashi I, Danjo K, Matsuzaka M, Kaneko S, Nakaji S.
    • Journal Title

      Ind Health

      Volume: 51

    • NAID

      130004828680

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evaliation of locomotive disability using loco-check: a cross sectional study in Japanese general population2013

    • Author(s)
      Sasaki Eiji
    • Journal Title

      J Orthop Sci

      Volume: 18 Issue: 1 Pages: 121-9

    • DOI

      10.1007/s00776-012-0329-2

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Coping behaviors in relation to depressive symptoms and suicidal ideation among middle-aged workers in Japan.2012

    • Author(s)
      Sugawara N, Yasui-Furukori N, Sasaki G, Tanaka O, Umeda T, Takahashi I, Iwane K, Matsuzaka M, Kaneko S, Nakaji S.
    • Journal Title

      J Affect Disord

      Volume: 142 Issue: 1-3 Pages: 264-268

    • DOI

      10.1016/j.jad.2012.05.011

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The relationship between exhaled carbon monoxide and human neutrophil function in the Japanese general population2011

    • Author(s)
      Mikami M, Takahashi I, Matsuzaka M, Danjo K, Yamai K, Inoue R, Iwane K, Umeda T, Nakaji S
    • Journal Title

      Luminescence

      Volume: 26(3) Pages: 162-6

    • Related Report
      2013 Final Research Report
  • [Journal Article] Prevalence of irritable bowel syndrome and its relation to lifestyle and depression quotient in a Japanese general population2011

    • Author(s)
      Kumeta K, Danjo K, Matsuzaka M, Takahashi I, Watanabe K, Iwane K, Tsuya, R, Umeda T, Sato K, Fukuda S, Nakaji S
    • Journal Title

      Hirosaki Med J

      Volume: 62 Pages: 144-65

    • NAID

      110008753993

    • Related Report
      2013 Final Research Report
  • [Presentation] 一般健常人の呼気中一酸化炭素濃度と生活習慣の関連2012

    • Author(s)
      岩根かほり、高橋一平、大久保礼由、梅田孝、中路重之
    • Organizer
      第4回日本安定同位体・生体ガス医学応用学会大会.シンポジウム生体ガス診断その医学応用の最先端
    • Place of Presentation
      日本慈恵会医科大学
    • Year and Date
      2012-10-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 閉塞性換気障害が歩行機能に及ぼす影響2012

    • Author(s)
      山居 聖典, 梅田 孝, 小室 輝明, 関根 陽平, 鷹野 都, 小川 武志, 溝口 絵里加, 中路 重之
    • Organizer
      日本体力医学会
    • Place of Presentation
      岐阜市
    • Related Report
      2012 Research-status Report
  • [Presentation] 一般健常人の呼気中一酸化炭素濃度と生活習慣の関連2012

    • Author(s)
      岩根かほり、高橋 一平、大久保礼由、梅田 孝、中路 重之
    • Organizer
      第4回 日本安定同位体・生体ガス医学応用学会大会
    • Place of Presentation
      東京都
    • Related Report
      2012 Research-status Report
  • [Presentation] 呼気中一酸化炭素濃度と各種他因子の関連について2011

    • Author(s)
      津谷亮佑 ,梅田孝 ,佐藤真樹 ,瀬尾京子 ,須田芳正 ,宮澤眞紀 ,熊坂義裕 ,中路重之
    • Organizer
      第81回日本衛生学会
    • Place of Presentation
      Web開催
    • Related Report
      2013 Final Research Report
  • [Presentation] 呼気中一酸化炭素濃度と各種他因子の関連について

    • Author(s)
      津谷亮佑, 梅田孝, 佐藤真樹,瀬尾京子, 須田芳正, 宮澤眞紀, 熊坂義裕, 中路重之
    • Organizer
      日本衛生学会
    • Place of Presentation
      紙上
    • Related Report
      2011 Research-status Report
  • [Remarks]

    • URL

      http://social.med.hirosaki-u.ac.jp/greeting.html

    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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