| Project/Area Number |
23650428
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATOH Makoto 筑波大学, 医学医療系, 教授 (50242409)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 青色LED / 睡眠障害 / エネルギー代謝 / 睡眠 / 睡眠時エネルギー代謝 / 居眠り / メラトニン / ヒューマン・カロリメータ |
|---|
| Research Abstract |
Evening light exposure,particularly, short wavelength blue light, increases subjective alertness, suppresses melatonin secretion and elicits changes in sleep architecture. Control of sleep/wakefulness is associated with the regulation of energy metabolism, it is plausible that evening blue light exposure might also affect energy metabolism during sleep. The present study assessed the effect of nocturnal blue light exposure on the control of sleep/wakefulness and energy metabolism until next noon. In a balanced cross-over design, 9 subjects sitting in a room-size metabolic chamber were exposed either to blue LED (wave length: 465 nm, intensity: 12.1 microW/cm2) or to no light for 2 h in the evening.
Exposure to low intensity blue light in the evening, which did not affect sleep architecture and metabolism during sleep, elicited drowsiness and suppression of energy metabolism in the following morning.
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