Disease-specific intestinal nutrient sensing mechanismand the development of special nutrition foods
| Project/Area Number |
23650482
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | The University of Tokushima |
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Principal Investigator |
YAMAMOTO Hironori 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (60314861)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 特殊栄養食品 / 栄養センシング / 生活習慣病 / 腸管遺伝子 / トランスクリプトーム / 栄養素センシング |
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| Research Abstract |
In this study, we established disease-specific intestinal nutrient sensing mechanism and a basis for the development of special nutritious food. I identified renal disease-specific nutrient sensor genes and gene database using DNA microarray analysis. In addition, administration of phosphorus restricted diet to renal failure animal model, found that to prevent the development of ectopic calcification and calcium metabolism abnormality, also effective in the prevention of renal anemia.
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Report
(3 results)
Research Products
(15 results)
