High-speed photonic sensor network using ultra-small waveguide devices to detect dangerous virus

• Project/Area Number: 23651138
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Microdevices/Nanodevices
• Research Institution: Hiroshima University
• Principal Investigator: ENAMI Yasufumi 広島大学, ナノデバイス・バイオ融合科学研究所, 特任教授 (90377474)
• Co-Investigator(Kenkyū-buntansha): SUYE Shin-ichiro 福井大学, 工学研究科, 教授 (90206376)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 光導波路 / フォトニクス / バイオ / ゾルゲルシリカ光導波路 / バイオフォトニックセンサ / センサネットワーク

Research Abstract

We detected organophosphorus compound using a planar waveguide sensors doped with green fluorescent proteins. The fluorescent power from the waveguide was reduced to half value within a minute when organophosphorus compound was applied on the waveguide. We also observed antibody-antigen reaction in the sol-gel silica thin-film. These results enabled the biophotonic waveguide sensor doped with living materials.

Research Products

• [Journal Article] Electro-optic polymer/TiO2 multilayer slot waveguide modulators (2012)
  • Author(s): Y. Enami
  • Journal Title: Applied Physics Letters Volume: 101 Issue: 12 Pages: 123509-123509
  • DOI: 10.1063/1.4754597
  • Peer Reviewed
• [Journal Article] Detection of organophosphorus compound based on a sol-gel silica planar waveguide doped with a green fluorescent protein and an organophosphorus hydrolase (2011)
  • Author(s): Y.Enami, K.Tsuchiya, S.Suye
  • Journal Title: Applied Physics Letters Volume: 98 Issue: 23 Pages: 233503-233503
  • DOI: 10.1063/1.3596448
  • Peer Reviewed
• [Presentation] Green FluorescentProtein-Doped Sol-gel Silica Planar Waveguide to Detect Organophosphorus Compound (2012)
  • Author(s): Y. Enami and S. Suye
  • Organizer: 3rdAsia Pacific Optical Sensors Conference (APOS2012)
  • Place of Presentation: Sydney, Australia
  • Year and Date: 2012-02-02
• [Presentation] “Electro-optic polymer/TiO2 multilayer slot waveguides for ultra-low voltage operation” (Invited) (2012)
  • Author(s): Y. Enami
  • Organizer: Collaborative conference on 3D & Materials Research (3DMR)
  • Place of Presentation: Seoul Korea
  • Invited
• [Presentation] “Hybrid electro-optic polymer/silica waveguide modulators and biophotonic sensor network based on sol-gel silica waveguides” (Invited) (2012)
  • Author(s): Y. Enami
  • Organizer: BIT’s 1st annual world congress of emerging InfoTech (WCEIT-2012), Dalian, China.
  • Place of Presentation: Dalian, China
  • Invited
• [Presentation] “Hybird electro-optic waveguide modulators for ultra-low power communications and interconnections”(Invited) (2012)
  • Author(s): Y. Enami
  • Organizer: EMN Fall meeting 2012
  • Place of Presentation: Las Vegas NV USA
  • Invited
• [Presentation] “Hybrid electro-optic polymer modulators and biosensors”(Invited) (2012)
  • Author(s): Y. Enami
  • Organizer: 2nd International Conference on Nanotek and Expo" (Nanotek-2012)
  • Place of Presentation: Philadelphia PA USA
  • Invited
• [Presentation] “Hybrid electro-optic polymer modulators and biophotonic sensors based on sol-gel silica waveguides” (2012)
  • Author(s): Y. Enami
  • Organizer: European Optical Society Annual Meeting
  • Place of Presentation: Aberdeen, Scotland, UK
• [Presentation] 「ハイブリッド型ポリマ光変調器」（招聘講演） (2012)
  • Author(s): 榎波康文
  • Organizer: 第3回 ディジタル信号処理による新しい光伝送技術”電子情報通信学会光通信システム研究専門委員会
  • Place of Presentation: 静岡
  • Invited
• [Presentation] 「ハイブリッド型ゾルゲルシリカ・電気光学ポリマ変調器」（招聘講演） (2012)
  • Author(s): 榎波康文
  • Organizer: 電子情報通信学会ソサイエティ大会シンポジウム
  • Place of Presentation: 富山
  • Invited
• [Presentation] "Electro-optic polymer modulators and biophotonic sensors based on sol-gel silica waveguides" (2012)
  • Author(s): Y. Enami and A. K-Y. Jen
  • Organizer: 招聘講演、電子情報通信学会総合大会(招待講演)
  • Place of Presentation: 岡山大学
• [Presentation] "Sol-gel waveguide for electro-optic modulators and biophotonic sensors"(invited) (2011)
  • Author(s): Y. Enami, J. Luo, and A. K-Y. Jen
  • Organizer: Collaborative conference on 3D & Materials Research (3DMR),(招待講演)
  • Place of Presentation: Jeju Korea
• [Presentation] "Detection of organophosphorus compounds based on a sol-gel silica planar waveguide doped with a green fluorescent protein and an organophosphorus hydrolase" (2011)
  • Author(s): Y. Enami,
  • Organizer: Applications of Light and Nanomaterilas Bioanalysis and Bioimaging, 2nd seminor on Nanoparticels and Single Molecules,(招待講演)
  • Place of Presentation: 産総研高松
• [Presentation] "Green Fluorescent Protein-Doped Sol-gel Silica Planar Waveguide to Detect Organophosphorus Compound" (2011)
  • Author(s): Y. Enami and S. Suye
  • Organizer: 3rd Asia Pacific Optical Sensors Conference (APOS2012)
  • Place of Presentation: Sydney, Australia
• [Remarks]
  • URL: http://www.sceng.kochi-tech.ac.jp/yenami/
• [Remarks] http://www.sceng.kochi-tech.ac.jp/yenami/
• [Remarks]
  • URL: http://home.hiroshima-u.ac.jp/yenami/
• [Patent(Industrial Property Rights)] 光変調器 (2012)
  • Inventor(s): 榎波康文
  • Industrial Property Rights Holder: 広島大学
  • Industrial Property Number: 2012-209631
  • Filing Date: 2012-09-24
• [Patent(Industrial Property Rights)] 光導波路スイッチ (2012)
  • Inventor(s): 榎波康文
  • Industrial Property Rights Holder: 広島大学
  • Filing Date: 2012-11-16
• [Patent(Industrial Property Rights)] 「光変調器」 (2012)
  • Inventor(s): 榎波康文
  • Industrial Property Rights Holder: 広島大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2012-209631
  • Filing Date: 2012-09-24
• [Patent(Industrial Property Rights)] ポリマ-光変調器の製造方法 (2011)
  • Inventor(s): 榎波康文、竹内浩史
  • Industrial Property Rights Holder: 広島大学、三菱レイヨン共同
  • Industrial Property Number: 2011-162418
  • Filing Date: 2011-07-25
• [Patent(Industrial Property Rights)] 光導波路型バイオセンサーおよびそれを備えたバイオセンサーシステム (2011)
  • Inventor(s): 榎波康文、末信一郎
  • Industrial Property Rights Holder: 榎波康文、末信一郎
  • Patent Publication Number: 2011-107071
  • Filing Date: 2011