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Study of neural network disturbance in dissociative amnesia by using neuroimaging and transcranial magnetic stimulation

Research Project

Project/Area Number 23653218
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Experimental psychology
Research InstitutionTohoku University

Principal Investigator

MORI Etsuro  東北大学, 大学院・医学系研究科, 教授 (30368477)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords神経機能画像学 / 認知科学 / 神経科学
Research Abstract

A fMRI experiment demonstrated that the activation of the prefrontal lobe elicited by deceptive behavior in a recognition memory task was increased by the memory materials was emotional. Another fMRI experiment demonstrated that the activation of the hippocampus elicited by the judgment of novelty, was altered depend on the context of the novelty. Furthermore, in a patient group of the left anterior thalamus infarcts, we examined the role of circuitry involving the thalamus and prefrontal cortex in memory by using MRI (diffusion tensor imaging and 3D MRI stereotaxic lesionlocalization) and PET.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (6 results)

All 2012 2011

All Journal Article (6 results) (of which Peer Reviewed: 5 results)

  • [Journal Article] Changing the criteria for old/new recognition judgments can modulate activity in the anterior hippocampus2012

    • Author(s)
      Hashimoto R, Abe N, Ueno A, Fujii T, Takahashi S, Mori E
    • Journal Title

      Hippocampus

      Volume: 22(2) Issue: 2 Pages: 141-148

    • DOI

      10.1002/hipo.20878

    • Related Report
      2012 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] The contribution of the dorsolateral prefrontal cortex to the preparation for deception and truth-telling.2012

    • Author(s)
      Ito A, Abe N, Fujii T, Hayashi A, Ueno A, Mugikura S, Takahashi S, Mori E.
    • Journal Title

      Brain Res.

      Volume: 1464 Pages: 43-52

    • DOI

      10.1016/j.brainres.2012.05.004

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuroanatomy of a neurobehavioral disturbance in the left anterior thalamic infarction2011

    • Author(s)
      Nishio Y, Hashimoto M, Ishii K, Mori E.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 82(11) Issue: 11 Pages: 1195-1200

    • DOI

      10.1136/jnnp.2010.236463

    • Related Report
      2012 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 記憶障害の神経基盤2011

    • Author(s)
      西尾慶之,森悦朗
    • Journal Title

      間脳性健忘.高次脳機能研究

      Volume: 31 Pages: 294-300

    • NAID

      10031128161

    • Related Report
      2012 Final Research Report
  • [Journal Article] The role of the dorsolateral prefrontal cortex in deception when remembe ring neutral and emotional events2011

    • Author(s)
      Ito A, Abe N, Fujii T, Ueno A, Koseki Y, Hashimoto R, Mugikura S, Takahashi S, Mori E
    • Journal Title

      Neuroscience Research

      Volume: 69(2) Issue: 2 Pages: 121-128

    • DOI

      10.1016/j.neures.2010.11.001

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] False item recognition in patients with Alzheimer's disease2011

    • Author(s)
      Nobuhito Abe
    • Journal Title

      Neuropsychologia

      Volume: 49(7) Issue: 7 Pages: 1897-1902

    • DOI

      10.1016/j.neuropsychologia.2011.03.015

    • Related Report
      2011 Research-status Report
    • Peer Reviewed

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Published: 2011-08-05   Modified: 2019-07-29  

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