• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Technical development of selective observation of proteins inliving cells by using ultraviolet resonance Raman spectroscopy

Research Project

Project/Area Number 23655012
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Physical chemistry
Research InstitutionOsaka University

Principal Investigator

MIZUTANI Yasuhisa  大阪大学, 理学研究科, 教授 (60270469)

Research Collaborator ISHIKAWA Haruto  大阪大学, 大学院・理学研究科, 講師 (40551338)
MIZUNO Misao  大阪大学, 大学院・理学研究科, 助教 (10464257)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords共鳴ラマン分光法 / in-vivo測定 / タンパク質構造
Research Abstract

In order to elucidate functional mechanism based on molecular structure of proteins, it is important to study not only purified proteins but also proteins in living cells. In this project, we developed measurement techniques to selectively observe Raman spectra of proteins in living cells with high sensitivity. We investigated dependences of overexpressed proteins and extent of overexpression on ultraviolet resonance Raman spectra of living cells.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (4 results)

All 2013 2012 Other

All Presentation (3 results) (of which Invited: 1 results) Remarks (1 results)

  • [Presentation] 時間分解共鳴ラマン分光法でタンパク質に起きていることを観る2013

    • Author(s)
      水谷泰久
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学 びわこ・くさつキャンパス
    • Related Report
      2012 Final Research Report
  • [Presentation] 時間分解共鳴ラマン分光法でタンパク質に起きていることを観る2013

    • Author(s)
      水谷泰久
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学 びわこ・くさつキャンパス
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 時間分解振動分光法を用いたヘムタンパク質の構造ダイナミクス研究2012

    • Author(s)
      水谷泰久
    • Organizer
      第25回生物無機化学夏季セミナー
    • Place of Presentation
      せせらぎ街道の宿「たかお」
    • Related Report
      2012 Final Research Report
  • [Remarks]

    • URL

      http://www.chem.sci.osaka-u.ac.jp/lab/mizutani/index-jp.html

    • Related Report
      2012 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi