| Project/Area Number |
23655078
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
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| Research Institution | Chiba University |
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Principal Investigator |
ARAI Takayoshi 千葉大学, 大学院・理学研究科, 教授 (80272483)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 触媒・化学プロセス / 光反応 / 不斉合成・反応 / 錯体化学 / 合成化学 / 選択的合成・反応 / 光励起 / 金属錯体 / 触媒 / 光学活性 / 配位子 |
|---|
| Research Abstract |
In this project, the metal complex-catalyzed asymmetric reactions were combined with photo-irradiation for supplying novel chiral compounds. For an example, the Friedel-Crafts/Henry reaction of indoles, nitroalkenes, and aldehydes, gave the three components coupling compounds having new contiguous stereogenic centers by the combination use of photo-isomerization of trans-nitroalkenes to the cis-nitoroalkenes. The method was also applicable to the [3+2]-cycloaddition of nitroalkenes with iminoesters. Moreover, the photo-irradiation was effective for controlling the activities of metal-proton cooperative catalyst.
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