Development of Biocompatible Co-continuous Membrane for Immune Depression
| Project/Area Number |
23655149
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemistry related to living body
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| Research Institution | Kyoto Prefectural University |
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Principal Investigator |
HOSOYA Ken 京都府立大学, 大学院・生命環境科学研究科, 教授 (00209248)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 免疫 / 生体適合性 / 共連続体 / 移植 / 膵島 / 共重合体 / 糖尿病 / インシュリン / QOL |
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| Research Abstract |
Biocompatible, co-continuous membranes which excluded immune cells but crossed by oxygen, glucose, and insulin were developed. A co-continuous membrane derived from poly-ethylene glycol based monomer showed excellent biocompatibility and controlled adhesion of tissue, while good vascularization was observed in rat body. Asmall bag for subcutaneous implant was also experimentally produced.
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Report
(3 results)
Research Products
(31 results)
