| Project/Area Number |
23656198
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Power engineering/Power conversion/Electric machinery
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| Research Institution | Toyohashi University of Technology |
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Principal Investigator |
TAKASHIMA Kazunori 豊橋技術科学大学, 工学(系)研究科(研究院), 准教授 (60303707)
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| Co-Investigator(Kenkyū-buntansha) |
MIZUNO Akira 豊橋技術科学大学, 環境・生命工学系, 教授 (20144199)
KURITA Hirofumi 豊橋技術科学大学, 環境・生命工学系, 助教 (70512177)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | プラズマ / 殺菌 / ウイルス / 不活化 / 放電プラズマ / ラジカル計測 / 電子スピン共鳴(ESR) / プラズマジェット / バリア放電 / MS2ファージ / コートタンパク / RNA / φX174ファージ / 核酸 |
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| Research Abstract |
For the study of mechanism of plasma sterilization and / or inactivation of viruses, a simple experimental system using bacteriophage, which consists of nucleic acid and coat protein was developed. In this experimental system, coat protein and nucleic acids can be analyzed separately. Therefore it enables to determine which damage is more fatal to the phase activity -- damage on coat protein or damage on nucleic acid.
Experimental results suggest that inactivation of lambda phage using dielectric barrier discharge plasma can be ascribed to a damage on the coat protein rather than the nucleic acid.
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