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Study on inhibitory effect of high light on the cell growth and adaptation mechanism of cyanobacteria

Research Project

Project/Area Number 23656526
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Biofunction/Bioprocess
Research InstitutionOsaka University

Principal Investigator

SHIMIZU Hiroshi  大阪大学, 情報科学研究科, 教授 (00226250)

Co-Investigator(Kenkyū-buntansha) FURUSAWA Chikara  大阪大学, 情報科学研究科, 招へい教授 (00372631)
HIRASAWA Takashi  大阪大学, 情報科学研究科, 助教 (20407125)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords微細藻類 / DNAマイクロアレイ / 光合成 / 代謝反応モデル / 強光条件
Research Abstract

Effect of light irradiation strength on growth of cyanobacteria Synechocystis sp. PCC 6803 was investigated to establish a new strategy for creation of high light stress tolerant strain keeping high growth and production ability under high light condition. It was succeeded that the cell growth activity was quantitatively evaluated and DNA microarray analysis was performed under several light intensity conditions. It is expected that the results of analysis could provide a fundamental basis for design of high light tolerant strains of cyanobacteria for industrial purpose.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (24 results)

All 2013 2012 2011 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (14 results) Book (4 results) Remarks (3 results)

  • [Journal Article] Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions2013

    • Author(s)
      Katsunori Yoshikawa
    • Journal Title

      Biotechnology Journal

      Volume: 印刷中 Issue: 5 Pages: 571-580

    • DOI

      10.1002/biot.201200235

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp2011

    • Author(s)
      Katsunori Yoshikawa, Yuta Kojima, Tsubasa Nakajima, Chikara Furusawa, Takashi Hirasawa and Hiroshi Shimizu
    • Journal Title

      PCC6803, Applied Microbiology and Biotechnology

      Volume: 92:2 Issue: 2 Pages: 347-358

    • DOI

      10.1007/s00253-011-3559-x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC68032011

    • Author(s)
      Katsunori Yoshikawa
    • Journal Title

      Applied Microbiology and Biotechnology

      Volume: Vol. 92, No.2 Pages: 347-358

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Synechocystissp. PCC 6803 における進化実験による強光ストレス耐性株の獲得2013

    • Author(s)
      小川健一
    • Organizer
      第54回日本植物生理学会
    • Place of Presentation
      岡山大学津島キャンパス
    • Year and Date
      2013-03-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 微細藻類の細胞工場の実現に向けたシステムバイオロジー解析2013

    • Author(s)
      吉川勝徳
    • Organizer
      化学工学会第78 年会
    • Place of Presentation
      大阪大学豊中キャンパス
    • Year and Date
      2013-03-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Systems biology in Synechocystis sp2012

    • Author(s)
      Katsunori Yoshikawa
    • Organizer
      PCC 6803, Metabolic Engineering IX
    • Place of Presentation
      Le Bellevue Congress and Exhibition centre, Biarritz, France
    • Year and Date
      2012-06-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Genome Scale Metabolic Flux Design and Experimental Evaluation of Cellular Performance2011

    • Author(s)
      Hiroshi Shimizu
    • Organizer
      The 2nd iBioP Asian Symposium (iBioP2011)
    • Place of Presentation
      POSTECH (Pohang University of Science and Technology), Pohang, South Korea
    • Year and Date
      2011-12-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 異なる栄養条件下でのシアノバクテリアの網羅的遺伝子発現解析2011

    • Author(s)
      小川健一
    • Organizer
      第63回日本生物工学会大会
    • Place of Presentation
      東京農工大学
    • Year and Date
      2011-09-28
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of a Photosynthesis Inhibitor on Metabolic Flux Profile of Cyanobacterium Synechocystissp2011

    • Author(s)
      Tsubasa Nakajima
    • Organizer
      PCC 6803, International Union of Microbiological Societies2011 Congress(IUMS2011)
    • Place of Presentation
      Sapporo Convention Center
    • Year and Date
      2011-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Systems Metabolic Engineering for Bioproduction Development2011

    • Author(s)
      Hiroshi Shimizu
    • Organizer
      International Union of Microbiological Societies 2011 Congress(IUMS2011)
    • Place of Presentation
      Sapporo Convention Center
    • Year and Date
      2011-09-06
    • Related Report
      2012 Final Research Report
  • [Presentation] Systems Metabolic Engineering for Bioproduction Development2011

    • Author(s)
      Hiroshi Shimizu
    • Organizer
      International Union of Microbiological Societies 2011 Congress(IUMS2011)
    • Place of Presentation
      Sapporo Convention Center, Hokkaido (Japan)
    • Related Report
      2011 Research-status Report
  • [Presentation] Effect of a Photosynthesis Inhibitor on Metabolic Flux Profile of Cyanobacterium Synechocystis sp. PCC 68032011

    • Author(s)
      Tsubasa Nakajima
    • Organizer
      International Union of Microbiological Societies 2011 Congress(IUMS2011)
    • Place of Presentation
      Sapporo Convention Center, Hokkaido (Japan)
    • Related Report
      2011 Research-status Report
  • [Presentation] 異なる栄養条件下でのシアノバクテリアの網羅的遺伝子発現解析2011

    • Author(s)
      小川健一
    • Organizer
      第63回日本生物工学会大会
    • Place of Presentation
      東京農工大学(東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] Genome Scale Metabolic Flux Design and Experimental Evaluation of Cellular Performance2011

    • Author(s)
      Hiroshi Shimizu
    • Organizer
      The 2nd iBioP Asian Symposium (iBioP2011)
    • Place of Presentation
      POSTECH (Pohang University of Science and Technology), Pohang, (South Korea)
    • Related Report
      2011 Research-status Report
  • [Presentation] Systems biology in Synechocystis sp. PCC 6803

    • Author(s)
      Katsunori Yoshikawa
    • Organizer
      Metabolic Engineering IX
    • Place of Presentation
      Le Bellevue Congress and Exhibition centre, Biarritz, France
    • Related Report
      2012 Annual Research Report
  • [Presentation] 微細藻類の細胞工場の実現に向けたシステムバイオロジー解析

    • Author(s)
      吉川勝徳
    • Organizer
      化学工学会 第78年会
    • Place of Presentation
      大阪大学 豊中キャンパス
    • Related Report
      2012 Annual Research Report
  • [Presentation] Synechocystis sp. PCC 6803における進化実験による強光ストレス耐性株の獲得

    • Author(s)
      小川健一
    • Organizer
      第54回日本植物生理学会
    • Place of Presentation
      岡山大学 津島キャンパス
    • Related Report
      2012 Annual Research Report
  • [Book] Systems Metabolic Engineering, Chapter32012

    • Author(s)
      Katsunori Yoshikawa
    • Publisher
      Springer
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Book] 生物工学会誌2012

    • Author(s)
      吉川勝徳
    • Publisher
      公益社団法人日本生物工学会
    • Related Report
      2012 Final Research Report
  • [Book] 生物工学会誌2012

    • Author(s)
      吉川勝徳
    • Publisher
      公益社団法人 日本生物工学会
    • Related Report
      2012 Annual Research Report
  • [Book] 日経新聞2012

    • Author(s)
      清水浩
    • Total Pages
      14
    • Publisher
      日本経済新聞社
    • Related Report
      2012 Annual Research Report
  • [Remarks] 清水浩、バイオ素材から樹脂原料、日本経済新聞第14 面、2012 年

    • URL

      http://wwww-shimizu.ist.osaka-u.ac.jp

    • Related Report
      2012 Final Research Report
  • [Remarks] http://www-shimizu.ist.osaka-u.ac.jp/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www-shimizu.ist.osaka-u.ac.jp/

    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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