Process innovation of enzymatic saccharification using hydrophobic ionic liquids

• Project/Area Number: 23656531
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biofunction/Bioprocess
• Research Institution: Kyushu University
• Principal Investigator: KAMIYA Noriho 九州大学, 工学研究院, 教授 (50302766)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: セルロース / セルラーゼ / イオン液体 / バイオマス / 酵素糖化

Research Abstract

In the present study, we explored a new potential strategy for converting cellulosic biomass to sugars by using hydrophobic ionic liquids (ILs). To realize anaqueoushydrophobic IL two-phase systemfor enzymatic saccharification, we synthesized new ILs comprising functional groups that have ability to dissolve crystalline cellulose. Finally, we developed one potential two-phase system for a simultaneous pretreatment and enzymatic saccharification process of cellulosic biomass.

Research Products

• [Journal Article] Low melting point pyridinium ionic liquid pretreatment for enhancing enzymaticsaccharification of cellulosic biomass (2013)
  • Author(s): Uju, Nakamoto, A., Shoda, Y., Goto, M., Tokuhara, W., Noritake, Y., Katahira, S., Ishida, N., Ogino, C. and Kamiya,N
  • Journal Title: Bioresource Technology Volume: Vol. 135 Pages: 103-108
• [Journal Article] Peracetic acid-ionic liquid pretreatment to enhance enzymatic saccharification of lignocellulosic biomass (2013)
  • Author(s): Uju, Abe, K., Uemura, N., Oshima, T., Goto, M. and Kamiya,N
  • Journal Title: Bioresource Technology Volume: Vol. 138 Pages: 87-94
• [Journal Article] Low melting point pyridinium ionic liquid pretreatment for enhancing enzymatic saccharification of cellulosic biomass (2013)
  • Author(s): Uju et al.
  • Journal Title: Bioresource Technology Volume: not assigned Pages: 103-108
  • DOI: 10.1016/j.biortech.2012.06.096
  • Peer Reviewed
• [Journal Article] Peracetic acid-ionic liquid pretreatment to enhance enzymatic saccharification of lignocellulosic biomass (2013)
  • Author(s): Uju et al.
  • Journal Title: Bioresource Technology Volume: not assigned Pages: 87-94
  • DOI: 10.1016/j.biortech.2013.03.147
  • Peer Reviewed
• [Presentation] Enzyme engineering with the aid of ionic liquid (2012)
  • Author(s): Noriho Kamiya
  • Organizer: The 90th Anniversary Annual Meeting of Society for Biotechnology, Japan
  • Place of Presentation: 神戸
  • Year and Date: 2012-10-24
• [Presentation] セルロース系バイオマス高効率分解に向けた酵素工学的アプローチ (2012)
  • Author(s): 神谷典穂
  • Organizer: トークシャワー・イン・九州2012
  • Place of Presentation: 福岡
  • Year and Date: 2012-09-06
• [Presentation] Potential of Ionic Liquids Pretreatment on Lignocellulosic Biomass for Efficient Enzymatic Saccharification (2011)
  • Author(s): Noriho Kamiya, Uju, Wataru Tokuhara, Yoshiyuki, Noritake, Nobuhiro Ishida, Masahiro Goto
  • Organizer: The 17th Symposium of Young Asian Biochemical Engineers' Community
  • Place of Presentation: 韓国
  • Year and Date: 2011-10-07
• [Presentation] 新規疎水性イオン液体による酵素糖化促進効果の解析 (2011)
  • Author(s): 庄田靖宏、後藤雅宏、石田亘広、神谷典穂
  • Organizer: 第63回 日本生物工学会大会
  • Place of Presentation: 東京
  • Year and Date: 2011-09-26
• [Presentation] Enzymatic Hydrolysisof Cellulosic Biomass in Aqueous-Ionic Liquid Media (2011)
  • Author(s): Noriho Kamiya, Masahiro Goto, KazunoriNakashima, Nobuhiro Ishida
  • Organizer: 第6回 日中化学工学シンポジウム
  • Place of Presentation: 中国
  • Year and Date: 2011-06-21
• [Presentation] Enzymatic Hydrolysisof Cellulosic Biomass in Aqueous-Ionic Liquid Media (2011)
  • Author(s): Noriho Kamiya, Masahiro Goto, Kazunori Nakashima, Nobuhiro Ishida
  • Organizer: 第6回 日中化学工学シンポジウム
  • Place of Presentation: 中国、武漢
• [Presentation] Potential of Ionic Liquids Pretreatment on Lignocellulosic Biomass for Efficient Enzymatic Saccharification (2011)
  • Author(s): Noriho Kamiya, Uju, Wataru Tokuhara, Yoshiyuki Noritake, Nobuhiro Ishida, Masahiro Goto
  • Organizer: The 17th Symposium of Young Asian Biochemical Engineers′ Community
  • Place of Presentation: 韓国、仁川
• [Presentation] Enzyme engineering with the aid of ionic liquid
  • Author(s): Noriho Kamiya
  • Organizer: The 90th Anniversary Meeting of SBJ
  • Place of Presentation: Kobe
  • Invited