Development of a new screening method to isolate the genes encoding RNA editing enzyme
| Project/Area Number |
23657003
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Nagoya University |
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Principal Investigator |
SUGITA Mamoru 名古屋大学, 遺伝子実験施設, 教授 (70154474)
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| Co-Investigator(Renkei-kenkyūsha) |
AOKI Setsuyuki 名古屋大学, 大学院・情報科学研究科, 准教授 (30283469)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | RNA 編集 / 葉緑体 / ミトコンドリア / ヒメツリガネゴケ / 逆遺伝学 / ペンタトリコペプチドリピートタンパク質 / PPRタンパク質 / RNA編集 / RNAスプライシング / RNAi法 / 葉緑体形質転換 |
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| Research Abstract |
In chloroplasts and mitochondria, RNA editing frequently occurs in many transcripts of most terrestrial plants. RNA editing is an enigmatic phenomenon in which specific cytidines (C) in the transcripts are changed to uridines (U). Since C-to-U RNA editing was discoveredin plant organelles 20 years ago, the RNA editing enzyme or factors remain to be identified. In this study, we have identified several novel RNA editing factors using a model plant, Physcomitrella patens.
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Report
(3 results)
Research Products
(30 results)
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[Journal Article] DNA packaging proteins Glom and Glom2coordinately organize the mitochondrial nucleoid of Physarum polycephalum.2011
Author(s)
Itoh, K., Izumi, A., Mori, T., Dohmae, N., Yui, R., Maeda-Sano, K., Shirai, Y., Kanaoka, M. M., Kuroiwa, T., Higashiyama, T., Sugita, M., Murakami-Murofushi, K., Kawano, S. and Sasaki, N
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Journal Title
Mitochondrion
Volume: 11(4)
Pages: 575-586
Related Report
Peer Reviewed
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