Reactivation of latently infected virus as a novel non-invasive stress marker
Project/Area Number |
23657170
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Applied anthropology
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Research Institution | The University of Tokyo |
Principal Investigator |
ISHIDA Takafumi 東京大学, 理学(系)研究科(研究院), 教授 (20184533)
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Research Collaborator |
TADAKARA Gento 東京大学, 大学院・理学系研究科, 博士課程
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Project Period (FY) |
2011 – 2012
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | ストレス評価 / ウイルス / 非侵襲 / ストレスマーカー / 社会的ストレス / アミラーゼ / 潜伏ウイルス / 再活性化 / ストレス指標 / 人類 / 霊長類 |
Research Abstract |
To search for novel non-invasive stress marker(s), reactivation of latently infected ubiquitous viruses and salivary alpha-amylase were monitored. The concentrations of salivary alpha-amylase among several animals such as elephants, chimpanzees, horses, were measurable with a simple machine produced for human amylase monitoring. Shedding pattern of the human gamma-herpesvirus (EBV) into saliva delayed the changes of alpha-amylase concentration; reactivation of EBV (or gamma-herpesvirus) is considered to be a medium-range stress marker.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Human papillomavirus genotype and cervical cancer in Northeast Thailand.2014
Author(s)
Natphopsuk, S., Settheetham-Ishida, W., Pientong, C., Sinawat, S., Yuenyao, P. and Ishida, T.
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Journal Title
Asian Pacific Journal of Cancer Prevention
Volume: 15
Related Report
Peer Reviewed
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[Journal Article] Extra-pair paternity confirmed in wild white-handed gibbons2013
Author(s)
Barelli, C., Matsudaira, K., Wolf, T., Roos, C., Heistermann, M., Hodges, K., Ishida, T., Malaivijitnond, S. and Reichard, U.H
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Journal Title
American Journal of Primatology
Volume: 75
Issue: 12
Pages: 1185-1195
DOI
Related Report
Peer Reviewed
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[Journal Article] The role of uncoupling protein 2 and 3 genes polymorphism and energy expenditure in obese Indonesian children2013
Author(s)
Mexitalia, M., Yamauchi, T., Utari, A., Sjarif, D R., Subagio, H W., Soemantri, A. and Ishida, T
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Journal Title
Journal of Pediatric Endocrinology
Volume: 26
Issue: 5-6
Pages: 441-447
DOI
Related Report
Peer Reviewed
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[Journal Article] Extra-pair paternity confirmed in wild white-handed gibbons.2013
Author(s)
Barelli, C., Matsudaira, K., Wolf, T., Roos, C., Heistermann, M., Hodges, K., Ishida, T., Malaivijitnond, S. and Reichard, U.H.
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Journal Title
American Journal of Primatology
Volume: 75
Pages: 1185-1195
Related Report
Peer Reviewed
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[Journal Article] Risk factors for cervical cancer in northeastern Thailand : detailed analyses for the sexual and smoking behaviors2012
Author(s)
Natphopsuk, S., Settheetham-Ishida, W., Sinawat, S., Pientong, C., Yuenyao, P. and Ishida, T
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Journal Title
Asian Pacific J. Cancer Prev
Volume: 13
Pages: 5489-5495
Related Report
Peer Reviewed
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[Journal Article] Lineage-specific evolution of T-cell immunoglobulin and mucin domain 1 gene in the primates2012
Author(s)
Ohtani, H., Naruse, T.K., Iwasaki, Y., Akari, H., Ishida, T., Matano, T. and Kimura, A
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Journal Title
Immunogenetics
Volume: 64
Issue: 9
Pages: 669-678
DOI
Related Report
Peer Reviewed
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[Journal Article] The unstable CCTG repeat responsible for myotonic dystrophy type 2 originates from an AluSx element insertion into an early primate genome2012
Author(s)
Kurosaki, T., Ueda, S., Ishida, T., Abe, K., Ohno, K. and Matsuura, T
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Journal Title
PLos One
Volume: 7
Issue: 6
Pages: e38379-e38379
DOI
Related Report
Peer Reviewed
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[Journal Article] (2012) : Hepatitis E virus outbreak in monkey facility, Japan2012
Author(s)
Yamamoto, H., Suzuki, J., Matsuda, A., Ishida, T., Ami, Y., Suzaki, Y., Adachi, I., Wakita, T., Takeda, N., Li, T.-C
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Journal Title
Emerging Infectious Diseases
Volume: 18(12)
Pages: 2032-2034
URL
Related Report
Peer Reviewed
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[Journal Article] High prevalence of an anti-hypertriglyceridemic variant of the MLXIPL gene in Central Asia2011
Author(s)
Nakayama K, Yanagiswa Y, Ogawa A, Ishizuka Y, Munkhtulga L, Charupoonphol P, Supannnatas S, Kuartei S, Chimedregzen U, Koda Y, Ishida T, Kagawa Y, Iwamoto S
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Journal Title
J Hum Genet
Volume: 56
Issue: 12
Pages: 828-833
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] Human papillomavirus genotype and cervical cancer in Northeast Thailand
Author(s)
Natphopsuk, S., Settheetham-Ishida, W.,Pientong,C., Sinawat, S., Yuenyao, P. and Ishida, T
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Journal Title
Asian Pacific Journal of Cancer Prevention
Volume: (in press)
Related Report
Peer Reviewed
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[Presentation] Current advances in gibbon phylogeny2012
Author(s)
Matsudaira, K. and Ishida, T
Organizer
The 3rd International Symposium on Southeast Asian Primates Research : Diversity and Evolution of Asian Primates
Place of Presentation
Bangkok, Thailand
Year and Date
2012-08-25
Related Report
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