Development of novel rice blast control system, which suppresses mutations in the pathogen
Project/Area Number |
23658038
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Plant pathology
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Research Institution | Hokkaido University |
Principal Investigator |
SONE Teruo 北海道大学, (連合)農学研究科(研究院), 准教授 (00333633)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | イネ / いもち病 / DNA修復 / 複合体 / 突然変異 / スクリーニング / いもち病菌 / DNA組換え修復 / 阻害剤 / ポジティブスクリーニング / バイオテクノロジー / 菌類 / 組換え修復 |
Research Abstract |
Rice blast is the most important disease of rice. One of the big problem in rice blast control is the mutation of pathogen that enables pathogens to overcome rice blast resistance. Mutations in rice blast fungus is mostly occur through DNA recombinations. This study aimed to develop a novel rice blast control strategy, which suppresses mutations in the pathogens, by studying the DNA recombination proteins in the pathogen. Results of this study indicated that DNA recombination is very important for the pathogen to cause the disease. DNA recombination proteins works as a complex will be a target for controlling the disease and suppressing the mutations. In this study, we also developed a screening system for inhibitors for protein-protein interaction.
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Report
(4 results)
Research Products
(17 results)