Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Research Abstract |
There have been reported many natural and synthetic bioactive compounds. However, it is usually not easy to identify their target molecules and/or target pathways. T o overcome this difficulty, we tried to construct a semi-genome wide screen system using yeast as a model system. We show that semi-genome wide system is effective for predicting the target pathway of a bioactive compound, while informatics analysis utilizing gene-gene network is indispensable for constructing a versatile prediction system.
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