Utility of highly reactive substrate peptide for transglutaminase for attachment
| Project/Area Number |
23658089
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied biochemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KAMIYA Noriho (50302766)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 酵素 / 基質ペプチド / 融合蛋白質 / タンパク質架橋化 / 蛋白質架橋 |
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| Research Abstract |
Transglutaminase is the enzyme family that catalyzes isopeptide bond formation between glutamine and lysine residues. We have obtained highly reactive substrate peptides which are available for immobilization of functional proteins via such substrate peptides and the enzyme. This project was attempted to use the peptide by characterization of the reaction between peptide and the enzyme.
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Report
(3 results)
Research Products
(28 results)
