Immune regulation systems in milk
| Project/Area Number |
23658108
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Food science
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| Research Institution | Gunma University |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2013-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ミルク / ペプチド / T細胞 / １型糖尿病 / 自己免疫疾患 / 鶏卵アレルギー / アレルギー疾患 / 免疫抑制剤 / 牛乳 / 1型糖尿病 / サイトカイン / 抗原提示細胞 / アレルギー / IL-10 |
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| Outline of Final Research Achievements |
A milk peptide fraction newly purified from cow's milk was found to highly suppress both allergen- and autoantigen-specific murine T cell responses, independent of their antigen specificity and MHC restriction. Our findings may be useful for preventing the allergies and autoimmune diseases.
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Report
(4 results)
Research Products
(6 results)
