| Project/Area Number |
23658215
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Iwate University |
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Principal Investigator |
KITA Kazumi 岩手大学, 農学部, 教授 (20221913)
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|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | ニワトリ / 筋芽細胞 / タンパク質合成 / グルコース / トリプトファン / アマドリ化合物 / β-カルボリン / PHP-THβC / グリケーション / 蛋白質合成 / 筋肉 / 腎臓 / 脾臓 |
|---|
| Research Abstract |
Firstly, the interactive effect of PHP-THβC on protein synthesis of chicken embryo myoblasts was examined. When fetal calf serum in the medium was 10%, protein synthesis was significantly increased by elevating PHP-THβC concentration more than 4 μM.
Secondly, the investigation to study the nutritional value for PHP-THβC revealed that PHP-THβC could not be a precursor for protein synthesis instead of tryptophan.
Thirdly, under normal condition, the concentrations of PHP-THβC and glucose-tryptophan Amadori product were approximately 1.5μM and 3.0 μM, respectively.
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