| Project/Area Number |
23658219
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Applied animal science
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
ROH Sanggun 東北大学, 大学院・農学研究科, 准教授 (90322130)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NISHIMORI Katsuhiko 東北大学, 大学院・農学研究科, 教授 (10164609)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 代謝 / 内分泌制御 / オキシトシン / オキシトシン受容体 / 脂肪細胞 / 乳腺上皮上皮細胞 |
|---|
| Research Abstract |
The aim of this study was to investigate 1) the expression of OXTR in adipose tissues and possible role in regulating lipid metabolism, and 2) the expression of OXTR during the differentiation of mammary epithelial cells. These results suggest 1) that up-regulation of OXTR during fat accumulation and adipocyte development may intensify the catabolic effects by oxytocin in adipose tissue to cause lipolysis, 2) OXTR expressionwas regulated by adiponectin and lactogenic hormones in bovine mammary epithelial cells.
|
