| Project/Area Number |
23658220
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Yamagata University |
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Principal Investigator |
ABE Hiroyuki 山形大学, 理工学研究科, 教授 (10375199)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Yuki 山形大学, 大学院・理工学研究科, 准教授 (00333328)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 光干渉断層画像化法 / 非侵襲計測 / 卵巣 / 生体機能評価 / 機能評価 |
|---|
| Research Abstract |
Optical coherence tomography (OCT) is analogous to ultrasound imaging except that it uses light instead of sound. OCT can provide a depth resolution of 1-20 um, which is one to two orders of magnitude higher than that of conventional ultrasound. OCT is a non-contact, non-invasive, fast imaging modality that provides real time, three-dimensional imaging capability. In this study, we examined, to the best of our knowledge, the first study that uses OCT for analysis of the developmental status of follicles in mouse ovary. The OCT image was identified each developmental stage from primary follicle (50 um in diameter) to antral follicle (350 um in diameter) in the ovary of 25.5-day-old mouse. Further we found time-varying OCT signals at the oocytes compared with around tissues.
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