| Project/Area Number |
23658235
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
FUKUMOTO Shinya 帯広畜産大学, 原虫病研究センター, 准教授 (50376422)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | マラリア / ベクター / 変異体 / ハマダラカ |
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| Research Abstract |
Genetic mutant is a powerful tool for the infectious disease research. Thus, the development of mutant screening system in the parasitic disease in veterinary field is desired. In this study, we tried to develop the transposon based random mutant screening system using murine malaria parasite as a model pathogen. As a result, we successfully established the gain-of function mutant parasite library system. Furthermore, with this system, we successfully could identify the genomic locus that highly concerns to vector transmission.
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