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A surrogate virus for researches on foot-and-mouth disease

Research Project

Project/Area Number 23658252
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied veterinary science
Research InstitutionThe University of Tokyo

Principal Investigator

HORIMOTO Taisuke  東京大学, 農学生命科学研究科, 准教授 (00222282)

Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsウイルス / レセプター / インテグリン / 口蹄疫 / 獣医学
Outline of Final Research Achievements

To examine whether wildlife may be responsible for spread of foot-and-mouth disease (FMD), I searched cell receptor molecules for FMD virus (FMDV) on the organs of Japanese wild deer. I identified integrin alpha V, beta 6, and beta 8, which are supposed to be the main receptor molecules for FMDV, suggesting that such deer are susceptible to FMDV, although I have not authenticated their functional roles using bovine rhinovirus 2 as a surrogate of FMDV.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (5 results)

All 2014 2013 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 1 results) Presentation (1 results)

  • [Journal Article] Administration of lasalocid-NA is preventive against Cryptosporidiosis of newborn calves.2014

    • Author(s)
      F. Murakoshi, M. Takeuchi, A. Inomata, T. Horimoto, M. Ito, Y. Suzuki, K. Kato.
    • Journal Title

      Veterinary Record

      Volume: 175 Issue: 14 Pages: 353-353

    • DOI

      10.1136/vr.102508

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Analyses of the binding between Theileria orientalis major piroplasm surface proteins and bovine red blood cells.2014

    • Author(s)
      Takemae H, Horimoto T, et al.
    • Journal Title

      Vet. Rec.

      Volume: 175 Issue: 6 Pages: 149-149

    • DOI

      10.1136/vr.102535

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of Cryptosporidium isolates from calves in Ishikari District, Hokkaido, Japan.2013

    • Author(s)
      Murakoshi F, Horimoto T, et al.
    • Journal Title

      J Vet Med Sci

      Volume: 75 Pages: 837-840

    • NAID

      130003362140

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Genomic and serological detection of bat coronavirus from bats in the Philippines.2012

    • Author(s)
      Tsuda S, TaniguchiS, et al.
    • Journal Title

      Archive of Virology

      Volume: 157 Issue: 12 Pages: 2349-2355

    • DOI

      10.1007/s00705-012-1410-z

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] フィリピンに生息するコウモリのコロナウイルス保有状況の調査2011

    • Author(s)
      津田峻平ら
    • Organizer
      第152回日本獣医学会
    • Place of Presentation
      大阪府立大学(大阪)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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